Kakaretso ea Lactoferrin

Lactoferrin (LF) ke protheine ea tlhaho ea lebese la mammary le ho bonts'a thepa ea anti-microbial. Ho tloha qalong ea eona ho 60s, ho bile le liphuputso tse ngata ho netefatsa boleng ba kalafo ba glycoprotein le karolo ea eona ea ho itšireletsa mafung.

Le ha bana ba banyenyane ba ka fumana tlatsetso ho tloha ho anyesa bo-'m'a bona, phofo ea lactoferrin e rekisoang e fumaneha bakeng sa lilemo tsohle.

1. Lactoferrin ke eng?

Lactoferrin (146897-68-9) ke glycoprotein e tlamang ea lelapa le fetisoang. Protheine ena e na le li-antibodies 'me e teng ka lebese la motho le la khomo. Ntle le moo, ke motsoako oa litšibollo tse ngata tsa tlhaho tse kang meokho, sesiti, maro a nko, lero la pancreatic le bile. Ka tlhaho 'mele o tla lokolla glycoprotein ka lebaka la ts'usumetso ea mokokotlo.

Pele u ka etsa lactoferrin reka, nka lekhasi ho hlahisa maikutlo ana ho bona hore na tlatsetso e na le molemo.

Li-lactoferrin tse ngata li fumaneha ka colostrum, e leng mokelikeli oa pele o khang o hlahisitsoeng kamora ho beleha. E tšeloa ka lebese nakong ea matsatsi a mabeli kapa a mararo ka mor'a ho beleha. Leha secretion ea colostrum e fihla haufi, lactoferrin e ngata e ntse e tla fumaneha ka lebese le fetohang.

Joale, u ntša lactoferrin joang ho bovine colostrum?

Ntumelle ho u nka ka mokhoa o otlolohileng oa ho khetholla lactoferrin.

Mohato oa pele o kenyelletsa ho arola Whey ho lebese. Whey ke ketso ea metsi e ntseng e le teng kamora ho pikitlanya kapa lebese le tlotsitsoeng ka motsoako oa acid. Ts'ebetso ea ho itšehla thajana e sebelisa tšebeliso ea "hydrophobic interaction chromatography" le chionatography ea ion-exchange e lateloang ke ho latellana ho latelang ka tharollo ea letsoai.

Colostrum ea letlalo e tsoa likhomong. E na le liprotheine, lithibela-mafu, liminerale, livithamini, lik'habohaedreite le mafura. Mekhahlelo ena e netefalitse boleng ba kalafo ba colostrum, ka hona, e hohela thahasello ho bo-rasaense ba etsang lipatlisiso lefapheng la bongaka.

Ka lebaka la hore litaba tsa lactoferrin lia fokotseha ha nako ea pelehi e eketseha, ho khothaletsoa lesea mohloli o mong. Ka mohlala, nka LF e tloaelehileng hang ka mor'a ho beleha e batla e le 7-14mg / ml. leha ho le joalo, mahloriso a ka theohela ho hoo e ka bang 1mg / ml ka lebese le holileng.

Haeba u batla ho itšireletsa ka "immunofactic" ea "lactoferrin", u lokela ho boloka chelete ka tlatsetso ea likhomo.

Phofshoana ea bongata bo entsoeng ka khoebo ea lactoferrin ke sehlahisoa sa polokelo ea likhomo. Leha ho le joalo, sehlahisoa sena e bile ntho e tšoenyang batho ba bang ba bonahalang ba tšoenyehile ka ho tšoaetsoa ke lefu la bohlanya ba likhomo. E re ke u tiisetse hore boemo bona ha bo fumanehe hangata. Ntle le moo, li-supplement tse ling tsa lesea la lactoferrin ke likarolo tsa raese e entsoeng ka liphatsa tsa lefutso, molemong oa batho ba sa mameleng lactose.

 

Melemo ea Lactoferrin ke Efe Bakeng sa Batho ba baholo le masea

 

2. Hobaneng u sebelisa Lactoferrin Powder joalo ka Tlatsetso, Melemo ea Lactoferrin e joalo?

Ho laola makhopho

Cutibacterium le propionibacterium li ikarabella bakeng sa makhopho a mangata. Lactoferrin e sebetsa ho nyenyefatsa libaktheria tsena tsa tšepe le ho fokotsa litlamorao.

Maemong a mang, li-radicals tsa mahala le mefuta ea oksijene e sebetsang e kenya letsoho ho senyeheng ha lisele le tšenyo ea DNA. Ka lebaka la khatello ea oxidative, ho ruruha ho ka hlaha le ho ama kholo ea makhopho. Ho latela bo-rasaense ba lipatlisiso, lactoferrin ke anti-oxidant e matla, ka hona, ke monyetla oa ho loantša li-radicals tsa mahala.

Ho nka lactoferrin hammoho le vithamine E le zinki ho tla fokotsa marulelo a makhopho le li-comedones ka nako e ka etsang likhoeli tse tharo.

Ntle le moo, ho ruruha ho hlohlelletsa ho thehoa ha makhopho le 'metso ka ho koala maqhubu. Mekhoa e khahlanong le ho ruruha ea lactoferrin e tiisa pholiso e potlakileng ea marapo.

Lingaka tsa meno li totobatsa taba ea hore bophelo ba hau ba mpa ke pontšo ea letlalo. Mohlala, haeba ts'oaetso ea hau ea ka mpeng e boreleli kapa e sa phetse hantle, ho sebelisa mefuta eohle ea litlolo tsa sefahleho kapa li-probiotic tsa boemo ba lefatše ho ke ke ha rarolla ho ruruha ha letlalo, lipapali, kapa eczema. Ho nka lactoferrin ho tla hlakola likokoana-hloko tse kotsi tse ka har'a pampitšana ea tšilo ea lijo ha li ntse li khothaletsa ts'ebetso ea limela tsa Bifidus tse sebetsang.

Ntle le ho phekola makhopho, lactoferrin e ile ea imolla matšoao a psoriasis mme ea potlakisa ho hlaphoheloa ho tsoa liso tsa leoto tsa neuropathic, tse atileng har'a bakuli ba nang le lefu la tsoekere.

Moemeli ea khahlanong le Microbial

Liphuputso tse ngata li tiisa hore Lactoferrin (LN) e thibela livaerase, libaktheria, likokoana-hloko le mafu a fungal ho hlasela 'mele. motsoako o sebetsa ka ho tlama likokoana-hloko tsena, ho senya sebopeho sa lisele tsa bona, le ho thibela li-receptor tsa sele.

Phuputsong e itseng, bo-ramahlale ba hlokometse seo lactotransferrin (LTF) e ne e sebetsa hantle ho thibela vaerase ea herpes ho feta mofuta oa motho. Liphuputso tsa inro le tsona li bonts'a hore tlatsetso ena e laola hantle litlamorao tsa HIV.

Ka tekanyetso e phahameng hanyane, lactoferrin e sebetsa ho sebetsana le bosholu ba Hepatitis C. Ho latela Patlisiso ea Hepatology, kalafo ena e eketsa polelo ea interleukin-18, protheine e ikarabellang bakeng sa ho khutlisa vaerase ea Hepatitis C. Bakeng sa katleho e phahameng, bakuli ba lokela ho nka ligrama tse 1.8 ho isa ho 3.6 tsa tlatsetso ka letsatsi. Lebaka ke hore litekanyetso tse tlase tsa lactoferrin li ke ke tsa etsa phapang ea bongata ba kokoana-hloko.

Ho na le likhopolo-taba, tse nkang LF e le kalafo ea tšoaetso ea helicobacter pylori. Ha o kenya tlatsetso ka kalafo ea hau ea liso, menyetla ke hore litlhare li tla sebetsa hantle. Taba ena e bile qhoebeshano ea masapo har'a bafuputsi kaha bongata bo lumela hore tšebeliso ea phofo ea lactoferrin e ke ke ea sebetsa ha ho se na litekanyetso tsa ngaka.

Taolo ea Iron Metabolism

Lactoferrin e ke ke ea laola feela ho tsamaisoa ha tšepe 'meleng empa e tla eketsa le ho monya ha eona.

Ho bile le phuputso e sa feleng ea bongaka e neng e batla ho bapisa ho sebetsa hoa LF khahlanong le ferrous sulfate ho khaello ea khaello ea methapo nakong ea kemero. Ho tloha tekong, lactoferrin e ipakile e le matla ho susumetsa sebopeho sa hemoglobin le lisele tse khubelu tsa mali.

Basali ba jang glycoprotein ba na le likarolo tse ngata tsa tšepe tse nang le litla-morao. Lactoferrin e sebetsa ho fokotsa monyetla oa ho senyeheloa ke mpa, pelehi pelehi le boima bo tlase ba 'mele.

Ka hona, ho hlakile hore ke tlatsetso e loketseng bakeng sa bo-mme le baimana ba lilemong tsa ho tsoala bana ba lahleheloang ke makhopho a itseng nakong ea ha ba le matsatsing a bona. Basebelisi ba meroho le ba fanang ka mali khafetsa ba ka rua molemo ho tlatsetso ea lactoferrin.

Pampitšana ea Bophelo bo botle ba 'Mele

Lactoferrin baby supplement e tlosa chefo mme e boloka mala a phetse hantle. E tlosa libaktheria tse kotsi, tse ikarabellang bakeng sa ho ruruha. Mohlala, likokoana-hloko tsena li ikarabella bakeng sa boholo ba linyeoe tsa gastroenteritis le enterocolitis, tse senyang marako a mala a lebisang lefung la pele ho nako. Haeba ka lebaka le itseng, lesea la hau ha le anyesele, ho khothaletsoa haholo hore o fetele ho bovine lactotransferrin (LTF).

 

Melemo ea Lactoferrin ke Efe Bakeng sa Batho ba baholo le masea

3. Melemo ea Lactoferrin ho Lesea

Lactoferrin baby supplement e sitisa kholo ea likokoana-hloko ka maleng a masea a sa tsoa tsoaloa. Likokoana-hloko tsena li kenyelletsa Escherichia coli, Bacillus stearothermophilus, Staphylococcus Albus, Candida albicans le Pseudomonas aeruginosa. Liphuputso tse 'maloa li tšehetsa taba ea hore ho ja letsatsi le leng le le leng tlatsetso ea lactoferrin bongata ho fokotsa menyetla ea noroviral gastroenteritis ho masea.

E ntse e le ka mpeng, LF e nts'etsa pele kholo ea lisele tsa endothelial ha e ntse e bua ka kholo ea methapo ea mahlo. Ka hona, hoa totobala hore tlatsetso ea lactoferrin e kanna ea ba lengolo bakeng sa mucus e senyehileng ea mala.

Ho anyesa ke mohloli o ka sehloohong oa tšepe bakeng sa neonates. Leha ho le joalo, lingaka tsa bana li khothaletsa hore tlatsetso ea tšepe e eketsehileng ea hlokahala kaha lebese la matsoele le na le liminerale tse nyane.

Ntumelle ke hlalose hore na hobaneng LF e le tlatsetso e ntle ho masea a pelehi le masea a hlahileng a le tlase haholo. Hangata, sehlopha sena se kotsing ea ho haelloa ke tšepe haholo. Ho fana ka tlatsetso ea lesea la lactoferrin ho tla eketsa hemoglobin le lisele tse khubelu tsa mali tsamaisong ea ngoana. Ho feta moo, lithuto li senola hore tlatsetso ea tšepe e matlafatsa kholo ea methapo ea lesea.

Ka linako tse ling, libaktheria tse kotsi tse kang E.coli li iphepa ka tšepe e fumanehang ka mpeng ea mala. Ho nka lactoferrin ho tla nyenyefatsa likokoana-hloko tsa tšepe le ho li senya ha u ntse u netefatsa hore moamoheli o fumana liminerale tsohle tse fumanehang.

LF e bapala karolo ea bohlokoa ntlafatsong ea masole a masea. Tse ling tsa lisebelisoa tsena tsa phofo ea lactoferrin li kenyelletsa keketseho ea ts'ebetso ea li-macrophages, li-immunoglobulin, lisele tsa NK, le li-lymphocyte tsa T, tse ikarabellang bakeng sa ts'ireletso ea mmele e sa sebetseng. Ho feta moo, ho tsamaisa LF ho fokotsa menyetla ea ho allergens.

 

4. Lactoferrin e ntlafatsa Sisteme ea 'Mele joang?

Mediates lipakeng tsa Adaptive le Innate Immune mesebetsi

Bakeng sa karabelo ea ka hare ea 'mele ea ho itšireletsa mafung, lactoferrin e sebetsa ka litsela tse ngata. Mohlala, e ntlafatsa mesebetsi ea lisele tsa tlhaho tse bolaeang (NK) le neutrophils. Protheine e matlafatsa phagocytosis mme e baka keketseho ea li-macrophages.

Bakeng sa karabelo e lumellanang, LF e thusa ho fetoheng ha li-T-cell le B-cell. Tabeng ea ho tšoaetsoa ho sa foleng, ts'ebetso ea boits'ireletso ea kahare le e sebetsang e tla kopana ho loants'oa ketsahalo eo.

Lactoferrin e laola tlhahiso ea li-cytokine tsa pro-inflammatory le interleukin 12, tse bonts'ang thepa ea ts'ireletso khahlano le likokoana-hloko tse kenang kahare.

Li-Mediates ho ea Systemic Inflammatory Response Syndrome (SIRS)

Karolo ea phofo ea lactoferrin ho hatella mefuta ea oksijene e sebetsang (ROS) e bile ea bohlokoa ho ithuteng kamano ea eona le ho ruruha le nts'etsopele ea mofets'e. Keketseho ea ROS e fetolela likotsi tse phahameng tsa maemo a ho ruruha ka lebaka la apoptosis kapa likotsi tsa cellular.

Ts'ireletso khahlanong le Likokoana-hloko

Matla a anti-microbial a lactoferrin a fokotsa ho ts'oaetso ea vaerase, vaerase, likokoana-hloko le mafu a fungal.

Likokoana-hloko lia atleha 'me li itšetleha ka tšepe hore e holise le ho phela. Ha ba hlasela moamoheli, LF e thibela bokhoni ba bona ba ts'ebeliso ea tšepe.

Nakong ea karolo ea pele ea ts'oaetso, lactoferrin (LF) e kenella ho loants'a litšusumetso tsa kantle ho naha ka litsela tse peli tse hlakileng. Protheine e ka thibela li-receptor tsa cellular kapa ea tlama vaerase, ka hona, ea thibela ho kenella ho eona. Liketso tse ling tse khahlanong le likokoana-hloko tsa lactoferrin li kenyelletsa ho senya tsela ea sele ea pathogen kapa ho thibela metabolism ea khabohaedreite.

Liphuputso tse 'maloa li tiisa hore phofo ea lactoferrin e sebelisoa tsamaisong ea vaerase ea Herpes, tšoaetso ea HIV, hepatitis C ea motho le B, ntaramane le hantavirus. Ntle le moo, tlatsetso e thibela ho ata ha alphavirus, rotavirus, papillomavirus ea batho le tse ling tse ngata.

Maemong a mang, Lactoferrin e kanna ea se ke ea ntša tšoaetso eohle empa o ka kholiseha hore e tla fokotsa boima ba palo ea vaerase e teng. Lithutong tse fetileng, LF e ne e atlehile ho thibela pseudovirus ea SARS. Kaha SARS-CoV-2 e oela sehlopheng se le seng le SARS-CoV, ho na le monyetla oa hore lactoferrin e ka fokotsa ts'oaetso ea COVID-19.

Le ha lingaka tsa meriana li lumela hore ho eketsa ts'ebetso ea hau ea 'mele ea ho itšireletsa mafung ha e sireletse motho ho coronavirus, tlatsetso ea lactoferrin e tla thusa ntoeng. Ntle le moo, litsebi tse tšoanang li hlokometse hore batho ba tsofetseng le batho ba nang le ts'oaetso e fokolang ba kotsing e kholo ea ho tšoaroa ke COVID-19.

 

5. Ts'ebeliso ea Powder ea Lactoferrin le Sesebelisoa

 Lactoferrin bongata ba phofo bo teng bakeng sa bo-rasaense ba lipatlisiso le litsebi tse batlang ho theha boleng ba eona ba bongaka 'meleng oa motho. E na le tebello e pharaletseng ea ts'ebeliso ea thibelo ea mafu, phepo e nepahetseng, lijo le litlolo tsa meriana, le litlolo.

Bakeng sa tlhahlobo ea hau le liteko tsa lab, etsa bonnete ba ho fumana motsoako ho tsoa barekisi ba phofo ea lactoferrin e sebetsang.

Lactoferrin phofo sebelisa ho phofo ea lebese la lesea

Lebese le phofo la masea le ntlafala khafetsa mabapi le ho bonahatsa biochemistry ea lebese la 'nete le tsoang ho mme. Lactoferrin ke palo ea bobeli ho fetisisa ea protheine lebeseng la mme. E tumme ka ho tlisa mefuta eohle ea melemo ho lesea ho kenyelletsa le ho tlama tšepe bakeng sa boits'ireletso ba mmele, thibelo ea mofets'e le ho khothaletsa masapo a phetseng hantle hara ba bang.

Lactoferrin ke karolo e ngata ea lebese la pele la mme le tsejoang e le colostrum. Colostrum e na le boima bo habeli ho mililita ho feta lebese la matsoele le holileng tsebong. Sena se bolela hore masea a manyane a manyane a hloka litekanyetso tse phahameng tsa lactoferrin bakeng sa nts'etsopele e ntle.

Ntlafatso ea sesole sa 'mele ea lesea e tšehelitsoe ke karolo ea Lactoferrin ka mokhoa oa lesea. Protheine e bapala karolo ea bohlokoa tsamaisong ea 'mele ea masea' me e emela sistimi ea ts'ireletso ea anti-virus le anti-microbial. Sesebelisoa sa mantlha sa anti-microbial hangata se tlisoa ke chelation ea li-iron-ion, tse bohlokoa bakeng sa kholo ea baktheria. Ntle le moo, ho lumeloa hore lactoferrin e sebetsa e le antioxidant e ka matlafatsang karabelo ea 'mele ea ho itšireletsa mafung ka ho thusa phapang, keketseho le ts'ebetso ea lisele tsa' mele.

 

Melemo ea Lactoferrin ke Efe Bakeng sa Batho ba baholo le masea

 

6. Litla-morao tsa Lactoferrin

Tšireletseho ea li-PFots ka lintlha tse 'maloa.

Lactoferrin litekanyo tse ngata li ka ba monate. Mohlala, ha tlatsetso e tsoa ho lebese la khomo, o ka e ja ka kholiseho ka selemo se le seng. Leha ho le joalo, ha sehlahisoa se tsoa ho raese, menyetla ke hore ho noa joala ka tatellano ka libeke tse peli ho tla hlahisa litšitiso tse mpe.

Litla-morao tse tloaelehileng tsa lactotransferrin (LTF) li kenyelletsa;

  • Letšollo
  • Ho lahleheloa ke takatso ea lijo
  • Litlhaku tsa letlalo
  • Ho tlosoa ha 'mele
  • Lipere

Ho fapana le litlatsetso tse ngata tsa kalafo, lactoferrin e bolokehile bakeng sa bo-mme ba lebelletsoeng le ba anyesang.

Ho feta litlamorao tsa lactoferrin, ho khothaletsoa tekanyetso ea lipakeng tsa 200mg le 400mg. U lokela ho e nka likhoeli tse peli ho isa ho tse tharo tse latellanang. Maemong a sa tloaelehang, nako e ka nyolohela ho likhoeli tse tšeletseng.

 

7. Ke mang ea ka fumanang Molemo ho Lactoferrin?

Bakhachane

Lactoferrin e thusa 'mè le lesea ka bobeli.

Nakong ea kemaro, ho tsamaisa tlatsetso ena ho ka ba le phello e ntle molemong oa lesea le boima ba lona ba tlhaho. Haeba mme a tsoela pele le moriana oa lactoferrin nakong ea kemolo, tlhahiso ea lebese la hae la matsoele e tla ntlafala haholo. Ntle le moo, lesea le ne le ka ithorisa ka tsela e sa tobang ka colostrum ho boloka boima ba 'mele bo phetseng hantle.

Masea le bana ba banyenyane ba sa tsoaloang kapa ba tsoakoa

Tlatsetso ea lactoferrin e tiisa hore lesea le ba le ts'oaetso e matla ea 'mele ea ho itšireletsa mafung ha le ntse le sireletsa tšenyo ea mali ea ka mpeng ho tsoa ho lintho tse ling. Ntle le moo, tlatsetso e sebetsa e le mokhoa oa ho khothatsa, o thusang mokokotlong oa pele oa ngoana. Metsoako ea masea e nang le "colostrum" e ngata e fumaneha ho barekisi ba phofo ea lehae ea inthaneteng le marang-rang.

Khaello ea Iron Anemia

Lactoferrin supplement e eketsa haholo maemo a hemoglobin, lisele tse khubelu tsa mali le ferritin. Leha batho ba bangata ba sebelisa ferrous sulfate ho loants'a khaello ea tšepe, lithuto tse ngata tsa lipatlisiso li tiisa hore lactoferrin e matla haholo.

Haeba u semela sa limela kapa u fana ka mali khafetsa, u tla hloka lijo tse nang le tšepe ho etsa maemo a tlase a hemoglobin le ferritin. Ho seng joalo, o ka etsa lactoferrin e ntle ho reka ho barekisi ba inthaneteng.

Batho ba nang le ts'oaetso e tlase

Lactoferrin e sireletsa 'mele khahlanong le likokoana-hloko ka ho hlakola likokoana-hloko tse tšoaetsanoang le ho thibela ho ata ha libaktheria le vaerase. K'hamphani e sebetsa ka thata ho feto-fetohang litsela tse tšoaeang tse lokelang ho shebella likarabo tsa sesole sa 'mele.

Lactoferrin e sebetsa e le mokena-lipakeng, ho tiisa le ho hokahanya tšebelisano lipakeng tsa mesebetsi e meng e itlhommeng pele ea ho itšireletsa mafung. Mohlala, e ntlafatsa mesebetsi ea phagocytic ka ho nyolla li-neutrophils le macrophages. Bakeng sa tsamaiso ea 'mele ea ho itšireletsa mafung, komporo ena e potlakisa phetoho ea lisele tsa T-B le B-cell, tse hlalosang ho itšireletsa mafung le selomong ka tsela e tšoanang.

8. Lactoferrin e nang le IgG

Joalo ka lactoferrin, IgG kapa immunoglobulin G ke protheine e sireletsang-likokoana-hloko e teng ka lebeseng la liphoofolo tse haufi.

Lithuto tse 'maloa li teng ho hlalosa kamano pakeng tsa lactoferrin le IgG.

Motsoako oa lactoferrin ho colostrum o phahame haholo ho feta oa IgG. Ho latela bo-rasaense ba lipatlisiso, lintlha tse 'maloa li ama bongata ba liprotheine tsena lebeseng.

Mohlala, lactoferrin le IgG ka bobeli li tsotella mocheso le pasteurization. Immunoglobulin G e ka 'na ea mamella kalafo ea mocheso ea ho fihlela ho 100 ° C empa ha e na metsotsoana e seng mekae. Ho fapana le moo, lactoferrin e fokotseha butle butle ka sekhahla sa mocheso ho fihlela se theoha ka botlalo ho 100 ° C.

Ka lebaka la lintlha tsena, o tlameha ho ba u hlokometse hore nako le mocheso o futhumatsang ke lintho tse ka nahanoang ka ho fetisisa ha ho sebetsoa lebese la neonatal. Kaha ho nona ha lebese ho entsoe ka phehisano ea lebese, batho ba bangata ba ikemisetsa ho omisa leqhoele.

The mahloriso ea Lactoferrin (146897-68-9) e se e le sehlohlolong ka mor'a ho beleha. Ha nako ea pelehi e ntse e eketseha, protheine ena e ea fokotseha butle-butle, mohlomong ka lebaka la phokotso ea colostrum. Ka lehlakoreng le leng, ho theoha ha maemo a immunoglobulin G hoo e batlang e sa tsotellehe nakong eohle ea pelehi.

Leha ho le joalo lactoferrin e ngata e oela lebeseng la mammary, khatello ea eona e ntse e tla phahama ho feta ea IgG. Taba ena e ntse e eme hore na ke colostrum, transitional, kapa lebese le holileng.

 

References

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  • Jeffrey, KA, et al. (2009). Lactoferrin e le Module ea 'Mele oa Tikoloho. Moralo oa Hona joale oa Lingaka.
  • Lepanto, MS, et al. (2018). Ho sebetsa hantle ha Ts'ebetso ea Oral ea Lactoferrin ho Phekolo ea Anemia le Anemia ea Tšoaetso ho Basali baimana le ba seng moimana: Phuputso e akaretsang. Meeli ea Immunology.
  • Goldsmith, SJ, et al. (1982). IgA, IgG, IgM le Lactoferrin Litaba tsa Lebese la Batho Nakong ea Tlholeho ea Peleho le Kameho ea ho Ts'ebetso le Ho Boloka. Journal ea Tšireletso ea Lijo
  • Smith, KL, Conrad, HR, le Porter, RM (1971). Lactoferrin le Igun Immunoglobulins tse tsoang ho Li-Gammine Mammary Glands tse amehang. Tlaleho ea Saense ea Lebese.
  • Sanchez, L., Calvo, M., le Brock, JH (1992). Karolo ea Likokoana-hloko ea Lactoferrin. Litlaleho tsa maloetse a bongoaneng bongoaneng.
  • Niaz, B., et al. (2019). Lactoferrin (LF): protheine ea tlhaho e khahlanong le Microbial. Koranta ea Machabeng ea Litheko tsa Lijo.