History

Pramiracetam phofo e tsoa ho lelapa la racetam. Ho sibolloa le ho ba teng ha eona ho qalile ka bo-1970, ka lebaka la Khampani ea Parke-Davis. Ke eng e bolellang nootropic ena ho tsoa ho li-racetams tse ling ke sebopeho sa eona sa limolek'hule le potency e phahameng.

Ha lilemo li ntse li feta, tšebeliso ea pramiracetam e bile khalefo eohle kalafo ea 'dementia', lefu la Alzheimer's, le mathata a mang a methapo ea methapo. Lilemong tsa morao tsa 80s le tse 90 tse fetileng, ho bile le liteko tse ngata tsa bongaka tse atlehileng, tse ileng tsa paka bonnete ba ts'ebetso ea pramiracetam ho khutlleng tahlehelo ea memori.

Bohlokoa ba sethethefatsi sena ha se thata joaloka li-nootropics tse ling. Mohlala, o ka khona reka pramiracetam phofo mme o e sebelise ntle le ho pikitla mahetla le ba boholong. Leha o ka se reke sehlahisoa se teng Canada, o ka se kenya ka molao bakeng sa ts'ebeliso ea hau. Europe, pramiracetam phofo e fumaneha feela tlasa lengolo le nepahetseng la ho laola dyslexia, 'dementia', Alzheimer's, le ADHD.

Hobaneng Pramiracetam e atile hakana?

Ts'ebeliso ea Pramiracetam e tsebahala sebakeng sa nootropics ka lebaka la potency ea eona. E sebetsa ka makhetlo a 30 ho feta piracetam. Setlhare se sebetsa ka boqheku le ka tekanyo e nyane haholo. E fumaneha haholo ka nako e telele ea halofo ea bophelo.

Taba ea hore u kanna oa se utloe litla-morao li etsa hore pramiracetam e be le boiphihlelo. Moriana ha o lemale ho hang. E bolokehile hape e mamelletse hantle mmeleng oa motho. Ho na le liteko tsa batho tse atlehileng tse netefatsang hore nootropic ena e sebetsa hantle. Ntle le moo, e lula hantle ka li-ranta tse ngata le tse ling nootropic phofo.

E 'ngoe hape ea pramiracetam ke hore ho fumana ho tšoana le ho reka marikhoe. Ha ho na melao e thata e hlokang hore o fuoe lengolo la ngaka, haholo US.

Pramiracetam e sebetsa joang?

Pramiracetam mafura a qhibilihang nootropic e kenella maling le mafura acid. E na le bioavailability e phahameng mme e tla fihla sehlohlolong sa tlhoro ka nako e ka bang metsotso e 30.

Setlhare sena se bohlale se baka ho eketsoa ha choline hippocampus. Ka hona, e laola ka mokhoa o sa tobang tokollo ea acetylcholine (ACh), e ikarabellang bakeng sa mesebetsi e mengata ea boko.

ACh e ikarabella bakeng sa ho theha le ho boloka memori ea nako e telele. Ntle le moo, neurotransmitter e lebisa ho eketseheng ha phallo ea mali a mokelikeli, e leng ntho e ntlafatsang kutloisiso.

Ts'ebeliso ea Pramiracetam ke eng?

Europe, ts'ebeliso ea Pramiracetam ea lumelloa ho phekola 'dementia'. Motsoako ona o bohlale oa neuroprotective o sebetsa hantle ho ntlafatsa mohopolo oa nako e telele le ho eketsa mesebetsi ea kelello. Ho la US le Canada, baithuti ba reka pramiracetam phofo bakeng sa ts'ebeliso ea off-label e le setheo sa ho ithuta ha ba batla ho etsa tlhahlobo e kholo.

Ho tloha ha e qala ho hlaha ka 1979, Pramiracetam esale e le lithethefatsi tse fanoang ho bakuli ba nang le maloetse a methapo ea methapo le methapo ea kelello. Mmaraka oa eona oa sepheo e ne e le haholo batho ba tsofetseng empa batho ba phetseng hantle ba ikopantseng le boiphihlelo ba pramiracetam, haholo bakeng sa ho eketsa tlhahiso ea bona lithutong le likhoebong tsa bona.

pramiracetam

Liphello le Melemo ea Pramiracetam

E ntlafatsa Memori

Pramiracetam e phahamisa memori ea ho bua. Bo-ramahlale ha baa ka ba leka li-nootropics tsena feela mefuteng ea murine empa le lithutong tsa batho.

Setlhare se sebetsa ka ho susumetsa hippocampus ho theha mehopolo e ncha, ho boloka ea khale, le ho fokotsa ho lebala. Boholo ba liithuti li thabela thabo ho Pramiracetam boiphihlelo ho matlafatsa mohopolo oa bona ha ba ithuta ka litlhahlobo.

Tsamaiso ea Maloetse a Kelello

Ho bile le liteko tse 'maloa tsa tleleniki tse bonts'ang katleho ea phofo ea Pramiracetam ho thibela maloetse a mpefatsang.

Melemo ea Pramiracetam bakuli ba nang le 'dementia' ka ho khutlisa amnesia le ho ntlafatsa ho hopola. Ka mohlala, Europe, lithethefatsi tse bohlale ke lengolo la molao bakeng sa ho laola lefu la Alzheimer's.

neuroprotection

etellang li-capsule tsa pramiracetam li tla sireletsa li-neuron tsa hau. Boholo ba nootropic bo khutlisetsa mathata a kelello ho bakuli ba nang le khatello ea kelello ea tlhaho ea letsoalo. Ho feta moo, e fokotsa ho fokotseha hoa kelello hoo e ka bang teng ka lebaka la ho pepesehela lithethefatsi tsa amnesic joalo ka scopolamine.

Bokhoni bo phahameng ba ho ithuta

Lithuto tse 'maloa li tiisa hore ho nka lithethefatsi tsa pramiracetam nootropic ho tla ntlafatsa thuto ea moea. Ke senotlolo sa kelello seo se tla etsa hore o utloisise lintho habonolo.

Nootropic e phahamisa tšebetso ea nitric oxide synthase ka hippocampus. Neurotransmitter ena e fokotsa mathata a kelello 'me e bapala karolo ea bohlokoa ho ithuteng le ho hopoleng. E sebetsa ka ho eketsa phepelo ea mali bokong, ka hona, e hlophisa mesebetsi ea methapo.

Pramiracetam e thusa tsamaiso ea methapo e bohareng ka ho nyolla tlhahiso ea acetylcholine, eo le eona e nang le letsoho la ho ithuta. Ntle le moo, o tla ba le ho hlaka, ho ela hloko le ho ba seli.

Mofuta o khothalletsoang oa Pramiracetam Powder ha o sebelisoa o le mong

Tekanyetso e tloaelehileng ea letsatsi le letsatsi ea pramiracetam e pakeng tsa 400mg le 600mg. Lithutong tse fumanehang tsa kliniki, lithuto li ka nka 1200mg ea lithethefatsi tse bohlale, ka ho khetheha ka mor'a lijo.

Kaha pramiracetam phofo e na le halofo e telele ea bophelo, o ka arola litekanyetso ka bobeli. Mokhoa ona o molemo haholo sehlopheng sa litlhare tsa meriana. Ho sebelisa litekanyetso tse tharo ka letsatsi e ka ba khetho e ntle empa u lokela ho etsa bonnete ba hore u fana ka taelo ea hau ea bongaka lihora tse 'maloa pele u robala. Ha u batle ho kena-kenana le morethetho oa hau oa sekareleta.

U ka reka Pramiracetam ka foromo ea capsule kapa pilisi. Phofo e qhibilihile, ka hona, e ke ke ea ba mohopolo o motle ho e kenyelletsa senoeng sa hao. Ntle le moo, o ka e qhala ka oli ea kokonate kapa lipid. Haeba u khathatsoa ke tatso ea punent, u lokela ho khetha li-capam tsa pramiracetam.

Joaloka mofuta o mocha, etsa bonnete ba hore u qala ho sebelisa lethal dose le tlase haholo ha u ntse u shebile 'mele oa hau bakeng sa mamello le litlamorao. Ka mor'a moo, o ka fetola litekanyetso ho ea li ratang mme a kenyelletsa tse ling pramiracetam mekotla.

Liphello tsa Pramiracetam tseo U Lokelang ho li Tseba

Ho fapana le li-racetams tse ling, litlamorao tsa Pramiracetam ha li na melaoana. Mmele wa hau o ka mamella tlatsetso ho sa tsotelehe hore na tekanyo e kae.

O kanna oa ba le matšoao a nakoana joalo ka hlooho ea pramiracetam, ho tsekela, ho hloka boroko, khatello ea ka mpeng, kapa ho ruruha. Leha ho le joalo, o ka qoba litla-morao tse bohloko ka ho fokotsa tekanyetso ea pramiracetam. Haeba u tšoaroa ke hlooho khafetsa, u ka 'na ua hloka ho itlama ka choline.

pramiracetam

Pramiracetam VS Piracetam

Piracetam ke pele ho tsohle tse ling tsa nootropics lelapeng la racetam ka tšimoloho ea eona e qalileng morao koana lilemong tsa bo-1970. Ka lehlakoreng le leng, pramiracetam e tsoa ho setlhare se bohlale.

Tsena tse peli tse maqhubu li na le litlamorao tse tšoanang. Empa, li fapana ka sebopeho sa limolek'hule le sebopeho sa tsona. Mohlala, pramiracetam setlhare se bohlale se na le makhetlo a 30 ebile se sebetsa hantle ho feta sa pele. Ho feta moo, nootropic e na le bioavailability e phahameng.

Keletso ea Stamiracetam Stack

Pramiracetam e hlahisa litlamorao tsa li-nootropics tse ling. Ke setlhare se nang le matla ka setheo se le seng empa o ka se paka ka li-riet tse ling le tlatsetso ea cholinergic.

Haeba u mocha sebakeng sa nootropics, ha ua lokela ho potlakela ho leka spamiracetam stack. Ntle le moo, moriana ona o bohlale o ntse o sebetsa hantle e le ntho e emeng e le 'ngoe. Hang ha sistimi ea hau e khona ho mamella litlamorao tsa pramiracetam, u tla lokoloha ho e kopanya le li-nootropics tse ling.

Li-supplement tsa Cholinergic li sebetsa hantle ho ena e le li-stacking ha li ntse li khaola lihlooho tsa pramiracetam.

Pramiracetam le Oxiracetam Stack

Ha ho pelaelo hore mokotla ona o tla eketsa bokhoni ba hao ba ho tsepamisa maikutlo, ho lula u falimehile, le ho ts'oarella ho tse fetileng.

Bakeng sa yuniti ka 'ngoe ea oxiracetam, u tla tlameha ho nka likarolo tse 'ne tsa li-capsule tsa pramiracetam. Nka ka mohlala, haeba mokotla oa hau o kenyelletsa tekanyetso ea 800mg ea pramiracetam, o lokela ho kenyelletsa 200mg ea oxiracetam.

  • Doi ea Letsatsi le letsatsi
  • 200mg ea oxiracetam
  • 800mg ea pramiracetam
  • 300mg ea choline

Pramiracetam le Aniracetam Stack

Ntle le ho ts'oara ts'ebetso ea ts'ebetso ea ts'ebetso ea boko, mekete ena e 'meli e tla felisa matšoenyeho, ho se tsotelle, le khatello ea maikutlo.

Aniracetam o na le nako e khuts'oane ea bophelo ha a bapisoa le molekane oa eona. Ka hona, e tla raha ka nako 'me e qale ho sebetsa pele u ka fumana melemo ea pramiracetam. Ho tsepamisa lintho tsena tse peli ho tla u thibela ho hola mamello ho nootropic e le 'ngoe.

Bakeng sa tekanyetso e 'ngoe le e' ngoe ea pramiracetam, o tla hloka tse ka bang 600mg ea aniracetam.

  • Doi ea Letsatsi le letsatsi
  • 600mg aniracetam
  • 400mg pramiracetam
  • Choline ea 300mg

Pramiracetam le Alpha GPC stack

Prack ena ea pramiracetam ke mohloli oa mantlha oa acetylcholine. Ha e matlafatse tšebetso ea boko feela empa e boetse e ntlafatsa mohopolo. Ho kopantsoe ha Alpha GPC ke hore e fumaneha ka bongata haholo kaha e tšela tšireletso ea mali le bokong ka nepo.

Ho tlatselletsa le GPC choline ho lokisa tse ling tsa litlamorao tsa Pramiracetam joalo ka hlooho. Ntle le moo, e nchafatsa li-neuron, e lokisa li-membrane tsa sele, 'me e hlophisa acetylcholine, e leng neurotransmitter ea bohlokoa ea memori.

Bakeng sa tekanyetso ea hau ea letsatsi le letsatsi, o tla hloka li-400mg tsa Alpha GPC tlatsetsa.

  • Doi ea Letsatsi le letsatsi
  • Tlatsetso ea 400mg Alpha GPC
  • 400mg pramiracetam

pramiracetam

Pramiracetam stur ea khofu

Coluracetam e khatholla kelello ea hau, e ntlafatsa ho thuisa, hape e khutlisa mohopolo oa nako e telele. E ntlafatsa ts'ebetso ea choline liseleng tsa neuronal. Ho feta moo, tlatsetso e ntle bakeng sa mahlo ha e ntse e lokisa methapo ea mahlo le tšenyo ea morao.

Bakeng sa mokotla oa hau oa pramiracetam, 30mg ea coluracetam ho lekane.

  • Doi ea Letsatsi le letsatsi
  • 30mg ea coluracetam
  • 400mg ea pramiracetam
  • Choline ea 300mg

Joang le ho reka pramiracetam phofo?

O ka reka nootropics pramiracetam ka phofo, capsule, kapa foromo ea pilisi. Setlhare se bohlale ha se so fumane tumello e loketseng ke FDA empa u ntse u ka se romella mabenkeleng a fumanehang. Ho na le 'maraka o mongata o motšo ho pota, kahoo, o hloka ho etsa bonnete ba hore o rekisetsa morekisi ea tsebahalang oa inthaneteng.

O ka re bankela taelo ea hau hobane re na le rekoto e netefalitsoeng ea ho rekisa nootropics e seng molaong. Re etsa liteko tse ikemetseng tsa laboratori ho bohle lihlahisoa tsa rona pele u li bapisetsa bareki ba rona ba bohlokoa.

Haeba u ntse u ipotsa hore na ke hobaneng li-capsules tsa pramiracetam li theko e boima ho feta li-racetam tse ling, ke tla u fa lebaka. Ho kopanya ntho ena ho haufi le papali ea Greek. Ts'ebetso ena e rarahane ho feta kamoo e leng ka eona nakong ea motsoako oa li-nootropics tse ngata.

fihlela qeto e

Nootropics pramiracetam ke lithethefatsi tse bohlale tse nang le matla bakeng sa ho holisa bokhoni ba hau ba ho ithuta. Ke khetho e ntle ho batho ba baholo le ba phetseng hantle ba batlang ho tsepamisa maikutlo, ho lula ba falimehile le ho ba le botsitso kelellong mesebetsing ea bona ea letsatsi le letsatsi. Tlatsetso e thusa bakuli ba nang le maemo a neurodegenerative ho khutlisa mohopolo oa bona o lahlehileng le ho boloka lintlha tsohle.

Li-nootropics tsohle li kile tsa lekoa pele ho liteko empa pramiracetam ke e 'ngoe ea tse' maloa tse lekiloeng litabeng tsa batho. Ho tsoa liphuputsong tse fapaneng tsa lipatlisiso, ho hlakile hore moriana o bolokehile hore o ka nooa le hore o mamelleha hantle 'meleng.

References
  1. McLean, A., Cardenas, DD, Burgess, D., Gamzu, E. (1991). Phuputso e laoloang ke placebo ea pramiracetam ho banna ba banyenyane ba nang le mathata a kelello le a kelello a bakoang ke ho lemala hloohong le lefu la hoaba. Boko Tse Kotsi.
  2. Corasaniti, MT, et al. (1995). Tsamaiso ea systemic ea pramiracetam e eketsa ts'ebetso ea nitric oxide synthase ho cortex ea motsoako. Neurology e Sebetsang.
  3. Tkachev, AV (2007). Ts'ebeliso ea li-nootropic agents kalafong e rarahaneng ea bakuli ba nang le khatello ea kelello. Likars'ka sprava.
  4. Pugsley, TA, et al. (1983). Mefuta e meng ea li-neurochemical ea pramiracetam (CI-879), moemeli ea matlafatsang oa kelello. Patlisiso ea Tlhabollo ea Lithethefatsi / Buka ea 3, Taba ea 5.
  5. Auteri, A., Blardi, P., Celasco, G., Segre, G., Urso, R. (1992). Pharmacokinetics ea pramiracetam ho baithaopi ba phetseng hantle ka mor'a taolo ea molomo. Koranta ea Machaba ea Patlisiso ea Clinical Pharmacology.
  6. Claus, JJ, et al. (1991). Litlhare tsa Nootropic ho lefu la Alzheimer's: kalafo ea matšoao le pramiracetam.
  7. Chang, T., Monyane, MR, Goulet, RJ, le Yakatan, JG (1985). Pharmacokinetics ea pramiracetam ea molomo ho baithaopi ba tloaelehileng. Tlaleho ea Clinical Pharmacology.

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