Ursodeoxycholic Acid Powder (128-13-2) Litlhaloso
| Name Product | Asiti Ursodeoxycholic |
| Lebitso la lik'hemik'hale | (R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
| Lehlalosi | UDCA;
Ursodiol; Tauroursodiol, Urosodeoxycholic Acid; Ursodeoxycholic acid (micronized); URSODEOXYCHOLIC ACID; URSODESOXYCHOLIC ACID; URSODEOXYCHOLOC ACID; |
| Nomoro ea CAS | 128-13-2 |
| InChIKey | RUDATBOHQWOJDD-UZVSRGJWSA-N |
| limolek'hule Formula | C24H40O4 |
| limolek'hule Wtse robeli | 392.57 |
| Masapo a monoisotopic | 392.29265975 |
| Melting Point | 203-204 °C (hote.) |
| Ho belisoa Poli | 437.26 ° C (tekanyo e boima) |
| segokanyipalo | 0.9985 (tekanyetso e thata) |
| Color | E tšoeu - e batla e le tšoeu |
| Solubility | ethanol: 50 mg/mL, e hlakile |
| Storage Tmocheso | 2-8 ° C |
| kopo | Ursodeoxycholic acid (UDCS) ke tšireletso ea lisele e sebelisoang haholo ho fokotsa mafu a sebete le a biliary. Ursodeoxycholic acid e ka sebelisoa ho ithuta mesebetsi ea eona e ikhethileng, ho tloha ho phokotso ea ho monya ha k'holeseterole, ho qhibiliha ha cholesterol ea nyooko ho isa ho khatello ea karabelo ea 'mele ea ho itšireletsa mafung. |
| Tlaleho ea Teko | fumaneha |
Ursodeoxycholic acid (UDCA), eo hape e tsejoang e le Ursodiol, ke bile acid e hlahisoang ka har'a lero la bile. E ile ea fumanoa ka lekhetlo la pele ka bile ea libere. Le hoja e se eona bile acid e ka sehloohong bathong, ho fumanoe hore e na le thepa ea bohlokoa ea phekolo. Nalane ea tšebeliso ea UDCA ho batho e ka saloa morao ho tloha mehleng ea khale Chaena.
Hajoale, UDCA ea kantle e sebelisoa lefatšeng ka bophara ho phekola le ho laola maemo a fapaneng a lefu la sebete, joalo ka mafu a nyooko (cholelithiasis), cholangitis ea mantlha ea biliary, le sclerosing cholangitis ea mantlha.
Ke hobane'ng ha u lokela ho nka ursodeoxycholic acid (ursodiol)?
Ursodeoxycholic acid (ursodiol) e thusa ho sireletsa li-hepatocyte le cholangiocyte le ho thibela tšenyo leha e le efe e eketsehileng ho tsona. UDCA phofo e boetse e bontšitsoe ho ntlafatsa bophelo bohle ba bakuli maemong a sa tšoaneng a hepatobiliary.
Ursodeoxycholic Acid(UDCA) Powder ke eng?
Joalokaha ho boletsoe ka holimo, phofo ea Ursodeoxycholic acid ke mofuta oa maiketsetso oa UDCA o sebelisetsoang ho phekola bakuli ba nang le maemo a sa tšoaneng a hepatobiliary. Ursodeoxycholic acid phofo e fumanoe e sebetsa ho Primary Biliary Cirrhosis 'me e bontšitsoe ho ntlafatsa bophelo ba bakuli. Ho fumana phofo e ntle ka ho fetisisa ea Ursodeoxycholic acid le ho fumana theko e ntle, mohlomong u hloka ho reka Ursodeoxycholic acid powder wholesale.
Lintho tsa Physicochemical tsa Ursodeoxycholic Acid
UDCA (3α, 7β-dihydroxy5β-cholanoic acid) ke bile acid ea bobeli. E thehoa ka mor'a ketso ea enzymatic ea likokoana-hloko tsa mala ho li-acid tsa mantlha tsa bile. Li-acid tsa mantlha tsa bile li entsoe ka karabelo ea enzymatic hydroxylation ea cholesterol.
UDCA phofo e bontšitsoe hore e na le thepa ea hepato-protective. Hangata, boholo ba li-acid tsa mantlha le tsa bobeli tse hlahisoang ke hydrophobic. Ka lehlakoreng le leng, Ursodeoxycholic acid powderis hydrophilic mme e fokotsa tšenyo ea oxidative e bakoang ke hydrophobic acid. Thepa ea hydrophilic ea phofo ea Ursodeoxycholic acid ke motheo oa phekolo ea UDCA ea molomo, e bonolo le e bonolo.
Ka mor'a ho nka UDCA e sa tloaelehang ka molomo, ho monya ho etsahala haholo ka maleng a manyenyane ka ho hasana ho se nang ionic. UDCA e ntan'o robeha ka har'a proximal jejunum ha e ntse e kopana le micelles ea endogenous bile acid. Ka mor'a hore e kene ka har'a sebete, ho kopana ha UDCA ho etsahala. Joale UDCA e kopanngoa le glycine le tekanyo e nyenyane ka taurine. Ebe e kenngoa ka mafolofolo ka har'a bile ka ho potoloha ha enterohepatic.
Li-conjugate tsa Ursodeoxycholic acid tse entsoeng ka tsela eo li monngoa haholo-holo ho tloha distal ileum. Nonabsorbed UDCA e fetela ka har'a kolone ebe e fetoloa ke libaktheria tsa mala ho lithocholic acid. Asiti ea Lithopolis hangata ha e qhibilihe ebile e ntšoa mantleng. Karolo e nyane ea asiti ea lithocholic e kenngoa. Ka mor'a moo, e hloekisoa sebeteng, e tšeloa ka har'a nyooko, 'me qetellong e ntšoe ka mantleng.
Ursodeoxycholic Acid / Ursodiol Powder Mechanism of Action
Ursodeoxycholic acid phofo e bontšitse hore e na le mekhoa e mengata ea liketso, 'me ho ntse ho e-na le mekhoa e ntseng e ithutoa.
Ursodeoxycholic acid powder e bontšitse hore e thusa haholo ho sireletsa kotsi ea cholangiocyte khahlanong le liphello tse chefo tsa bile acid, ho hlohlelletsa secretion ea biliary e sa sebetseng pele, ho susumetsa ts'ebetsong ea detoxification khahlanong le hydrophobic bile acids, kapa ho thibela apoptosis, ke hore, selefouno e ikemetseng. lefu la hepatocyte.
Ho ntse ho sa utloisisoe hantle hore na ke efe ea mekhoa ena e ikarabellang haholo-holo bakeng sa liphello tse molemo tsa UDCA. Ntle ho moo, tekanyo ea melemo e tsoang ho UDCA e boetse e itšetlehile ka boemo bo itseng ba motho le boemo ba lefu.
Ke Mehloli Efe e ka Sehloohong ea Ursodeoxycholic acid phofo Marakeng?
Leha batho ba hlahisa UDCA, e tlase haholo ho feta bile acid tse ling tse hlahisoang. Ka hona, patlisiso e 'ngoe e ntse e tsoela pele. Ho fihlela joale, tlhahiso ea phofo ea ursodeoxycholic acid ka libere e bile ka bongata bo boholo.
Kaha ho na le litlamorao tsa litokelo tsa liphoofolo le kotsi ea ho tsoma, ho ntse ho shejoa mehloli e meng. Har'a bona, phofo ea UDCA ea bovine e bontšitse liphello tse ntle. Mehloli e meng e kang tomoso le algae le eona e ntse e shejoa. Tlhahiso ea maiketsetso ea UDCA ho tsoa ho limolek'hule tse tlang pele le eona e na le thahasello e kholo. Leha ho le joalo, ho boetse ho nahanoa ka liphello tsa litšenyehelo. Ntlafatso ea morao-rao sebakeng sena e shebile mehloli ea limela e le mokhoa o mong. Ho na le li-synthetic ursodeoxycholic acid powder tse rekisoang, fumana mohloli oa 'nete oa ursodeoxycholic acid powder supplier, o hloka ho e ela hloko haholoanyane. 'Me li-supplement tsa ursodeoxycholic acid li fumaneha inthaneteng.
Melemo le Liphello tsa Ursodeoxycholic Acid Powder
Ke melemo efe ea ursodeoxycholic acid? UDCA phofo e bontšitse ntlafatso e kholo 'me e lekanyelitsoe ho maemo a sa tšoaneng a hepatobiliary. E sebelisoa ho phekola le ho laola maemo a fapaneng a hepatobiliary, joalo ka mafu a nyooko (cholelithiasis), cholangitis ea mantlha ea biliary, le primary sclerosing cholangitis.
E bontšitsoe hore e na le phello e ntle tsamaisong ea 'mele ea ho itšireletsa mafung, ho theola k'holeseterole, ho qhala majoe a gallbladder, ho sireletsa sebete, le ho fokotsa maemo a lipids maling ho bolela tse seng kae. Le hoja mokhoa o nepahetseng oo UDCA e etsang joalo ka oona e ntse e le sebaka sa lipatlisiso, mekhoa e tsebahalang e se e tšohliloe ka holimo.
Ursodeoxycholic acid phofo ke eng E sebelisoa bakeng sa?
Ursodeoxycholic acid (ursodiol) e sebelisoa haholo-holo bakeng sa mafu a fapaneng a sebete le a bile. Leha ho le joalo, tšebeliso ea eona ha e felle feela ka maemo a hepatobiliary ka se. Ka lilemo tsa lipatlisiso tse matla, phello e ntle ea UDCA ea ho phekola maemo a fapaneng e pakiloe. Sena se kenyelletsa ho qhala majwe a nyooko le ho thibela le ho alafa majwe a cholesterol. UDCA phofo e boetse e sebelisoa e le sesepa sa anionic bakeng sa lipatlisiso tsa biochemical, moemeli oa anti-cholelithiasis, anticonvulsant, le cytoprotective agent. Litšebeliso tse ling tsa phofo ea ursodeoxycholic acid e ntse e le sebaka sa thahasello lipatlisisong tse sa tšoaneng tse tsoelang pele le liteko tsa meriana.
Mokhoa oa ho nka Ursodeoxycholic Acid Powder?
Ursodeoxycholic acid supplement hangata ha e rekisoe ka k'haontareng 'me, hangata e hloka lengolo la ngaka. Pele o sebelisa UDCA, ho bohlokoa ho buisana le ngaka ea hau ka kotsi e ka bang teng khahlano le molemo. Hangata ngaka e tla buisana ka mela ea histori ea bongaka, haholo-holo mafu a hepatobiliary le histori ea allergic. Leha UDCA e sebelisoa bakeng sa mafu a sebete, ho na le mafu a mang a lefu la sebete moo tlhokomeliso e lokelang ho sebelisoa.
Ka hona, puisano e pharaletseng le ngaka ke ea bohlokoa ka ho fetisisa 'me ho feta moo haeba u na le histori ea bongaka ea nakong e fetileng hammoho le ascites (ho bokellana ha metsi ka har'a peritoneal cavity), ho tsoa mali (methapo e hōlang le ho tsoa mali), hepatic encephalopathy (boko). pathology ka lebaka la ho hloleha ha sebete), tšenyo ea sebete nakong e fetileng, ho kenya sebete, ho thibela ho tsoa ha biliary, mathata a biliary tract, le pancreatitis.
Ha lipuisano tsohle li sa bontše likotsi tse kholo, UDCA hangata e laeloa ka tsela e latelang:
Bakeng sa lefu la gallstone:
Batho ba baholo le bana ba lilemo tse 12 le ho feta-Tekanyetso ea ursodeoxycholic acid hangata ke 8 ho 10 milligrams (mg) ka kilogram (kg) ea boima ba 'mele ka letsatsi, e arotsoe ka litekanyetso tse peli kapa tse tharo.
Bana ba ka tlase ho lilemo tse 12-Sena hangata se khethoa ke ngaka.
Bakeng sa "biliary cirrhosis" ea mantlha:
Batho ba baholo - Hangata tekanyo ea 13 ho 15 milligrams (mg) ka kilogram (kg) ea boima ba 'mele ka letsatsi, e arotsoe ka litekanyetso tse peli ho isa ho tse' nè. Ngaka ea hau e ka fetola tekanyo ea hau ha ho hlokahala.
Bana- Sena se khethoa ke ngaka ka kakaretso
Bakeng sa thibelo ea li-gallstones nakong ea tahlehelo ea boima ba 'mele ka potlako:
Batho ba baholo-Tekanyetso ea ursodeoxycholic acid hangata ke 300 milligrams (mg) habeli ka letsatsi.
Bana ba ka tlase ho lilemo tse 12 - Hangata sena se khethoa ke ngaka.
Boholo ba nako, haeba tekanyo e le 'ngoe e hlolohetsoe, ho noa lethal dose kapele kamoo ho ka khonehang ho eletsoa haeba nako e tsoang ho lethal dose ea ho qetela e se e feta lihora tse 4. Ka makhetlo a mangata a fetotsoeng, ho buisana le ngaka hoa hlokahala.
UDCA e tlameha ho nkuoa ho latela lengolo la ngaka. Haeba ho na le overdose, ho na le monyetla o moholo oa hore tekanyetso e le 'ngoe e eketsehileng e ka baka kotsi. Leha ho le joalo, haeba ho na le overdose e kholo, ho molemo ho ikopanya le ngaka ea hau kapa ho etela sepetlele se haufi.
Joalo ka moriana o mong le o mong, kamehla ho na le litlamorao ho isa tekanyong e itseng. Ho molemo ho ikopanya le ngaka ea hau kapa sepetlele se haufi haeba ho na le litla-morao tse latelang tsa ursodeoxycholic acid:
Matšoao a tloaelehileng
Bohloko ba senya, moroto o nang le mali kapa o koahetsoeng ke maru, ho ntša metsi a chesang kapa a bohloko, ho tsekela, ho otla ha pelo ka potlako, takatso ea khafetsa ea ho ntša metsi, ho lla, ho opeloa ke mokokotlo kapa lehlakoreng, ho nyekeloa ke pelo ho matla, lekhopho la letlalo kapa ho hlohlona 'meleng oohle, bohloko ba ka mpeng, ho hlatsa, ho fokola.
Matšoao a fokolang a tloaelehileng
Ho ba le mantle a matšo, a sefubeng, mohatsela kapa feberu, ho khohlela, ho supa matheba a mafubelu letlalong, bohloko bo boholo kapa bo tsoelang pele ba ka mpeng, 'metso kapa litšoelesa tse ruruhileng, liso kapa liso kapa matheba a masoeu molomong kapa molomong, ho tsoa mali ho sa tloaelehang kapa matetetso, mokgathala kapa bofokodi bo sa tloaelehang.
Phokotso e akaretsang ea matšoao e bontšitsoe hore e hlahe ka hare ho libeke tsa 3-6 ho qala kalafo ka phofo ea UDCA. Nako ea phekolo e fapana ho ea ka motho ka mong. Ngaka e fanang ka litaelo e hlahloba boemo nako le nako. Ka hona, ts'ebetso ea nako e nepahetseng ke ea bohlokoa. Ursodeoxycholic acid phofo e fumanoe e sireletsehile ho batho ba 'nileng ba e nka ho fihlela likhoeling tsa 6 esita le ho batho ba e nkileng bakeng sa likhoeli tsa 48. Ka hona, ho bolokehile ho bolela hore phofo ea UDCA e bolokehile bakeng sa tšebeliso ea nako e telele, hafeela ho e-na le ts'ebetso ea nako e nepahetseng le liteko tse tloaelehileng tsa ts'ebetso ea sebete li etsoa ka nako.
Moriana o Molemo ka ho Fetisisa oa Mafu a Sebete ke Ofe?
Ha ho na pheko e nepahetseng ka ho fetesisa kapa puso e le 'ngoe ea ho thunngoa bakeng sa mafu ohle a sebete. Ursodeoxycholic acid powder, leha ho le joalo, e na le thuso ebile ha e felle feela maemong a fapaneng a lefu la sebete, joalo ka mafu a gallstone (cholelithiasis), cholangitis ea mantlha ea biliary, le primary sclerosing cholangitis.
A na nka Nka Ursodeoxycholic Acid ka Meriana e Meng?
UDCA e batla e le sethethefatsi se sireletsehileng. Leha ho le joalo, tlhokomeliso e lokela ho sebelisoa haeba meriana leha e le efe e nang le cholestyramine, colestimide, colestipol, aluminium hydroxide, le smectite e nkoa hammoho le UDCA hobane UDCA ea ho monya e senyehile ke tsona. Litšebelisano tsa lithethefatsi tsa metabolic le metsoako e entsoeng ke cytochrome P4503A li bonoa hammoho le lithethefatsi tse ling tse kang cyclosporin, nitrendipine le dapsone.
Na Ursodeoxycholic Acid Powder e Molemo Bakeng sa Sebete?
Ursodeoxycholic Acid Powder ka kakaretso e molemo bakeng sa sebete ka lebaka la liketso tsa eona tse sireletsang li-cholangiocyte le hepatocyte, tšireletso khahlanong le kotsi e tsoang liphellong tse chefo tsa bile acid, ho tsosoa ha secretion ea biliary, le ho susumetsa ts'ebetsong ea detoxification khahlanong le hydrophobic bile acid le ho thibela apoptosis, ke hore. , ho shoa ha lisele tse iketselitseng li-hepatocyte.
UDCA kapa Udiliv(lebitso la khoebo) e boetse e sebelisitsoe ho laola lefu la sebete sa mafura, haholo-holo Steatohepatitis e seng joala (NASH), e nang le liphello tse ntle haholo. Leha ho le joalo, lipatlisiso tse ling le litlhahlobo tsa meta lia hlokahala bakeng sa bonnete bo felletseng.
Phapang ke efe lipakeng tsa Ursodeoxycholic Acid(UDCA) le Chenodeoxycholic Acid(CDCA)?
UDCA le CDCA ka bobeli ke bile acid. Ho batho, UDCA le Chenodeoxycholic Acid (CDCA) lia hlahisoa. Leha ho le joalo, CDCA e hlahisoa ka bongata bo boholo. Ka bobeli UDCA le CDCA ke lihlahisoa tse senyang k'holeseterole, ho qala. CDCA ke bile acid ea mantlha, ke hore, e entsoe haholo ke sebete ho tsoa ho k'holeseterole, athe UDCA e hlahisoa ka lebaka la ho senyeha ha enzymatic ke libaktheria ka maleng.
Ka hona, maemong a lefu la gallstone, Ursodeoxycholic Acid (UDCA) e ne e sebetsa haholo ho feta CDCA mebusong e tlase le e phahameng.
Buy Asiti ea Ursodeoxycholic bongata ba phofo? | Where ho fumana molemo ka ho fetisisa Asiti ea Ursodeoxycholic moetsi oa phofo?
Bongata ba phofo ea Ursodeoxycholic acid bo ka rekoa inthaneteng ka liwebosaete tse fapaneng. Leha ho le joalo, u lokela ho ba hlokolosi mabapi le bonnete le boleng ba sehlahisoa. Tlhahlobo e qaqileng ea metsoako e sebetsang le mahloriso e tlameha ho etsoa pele. Phcoker ke moetsi ea molemo ka ho fetisisa oa ursodeoxycholic acid powder.
Ursodeoxycholic Acid: The Ultimate FAQ Guide
Na ursodiol e hlile e sebetsa?
Ee. Ursodiol e bontšitse hore e sebetsa hantle ho alafong maemo a fapaneng a lefu la sebete, ha feela ho ka ba le tlhahlobo ea kapele, 'me kalafo e qala kapele kamoo ho ka khonehang.
Ke sethethefatsi sefe se qhibilihang seretse sa gallbladder?
Phofo ea UDCA e 'nile ea pakoa hore e sebetsa hantle ho qhaqha gallbladder sludge.
Na ursodiol e ka baka boima ba 'mele?
UDCA phofo e ka baka boima ba 'mele, haholo-holo likhoeling tsa pele tsa 12 tsa phekolo.
Na ursodiol ke steroid?
Li-steroids li arotsoe ka mefuta e fapaneng. Ka bobeli li-steroids le bile acid li entsoe kapa ke lihlahisoa tsa metabolism ea k'holeseterole. Liphuputso tse ling li bonts'itse sebopeho se kang steroid sa bile acid ho laola tšebetso ea 'mele ea letsatsi le letsatsi. Leha ho le joalo, lipatlisiso tse eketsehileng tšimong lia hlokahala bakeng sa bopaki bo tiileng.
Na ursodiol ke immunosuppressant?
UDCA e fumanoe e na le thepa e 'ngoe ea immunosuppressant.
Na ursodiol e fokotsa bile acid?
UDCA e bonts'itse hore e sebetsa hantle ho hlohlelletsa detoxification khahlanong le hydrophobic acid. Ursodeoxycholic acid phofo e boetse e bontšitsoe ho fokotsa hydrophobic acid. Leha ho le joalo, lipatlisiso tse ling li ntse li hlokahala.
Na ursodiol e ntlafatsa li-enzyme tsa sebete?
UDCA e ipakile e sebetsa hantle ho ntlafatseng li-enzyme tsa sebete ho mafu a fapaneng a sebete.
Ke ursodeoxycholic acid phofo molemo bakeng sa liphio?
Lipatlisiso tse entsoeng ka likhoto ha lia ka tsa bontša kotsi ka phofo ea UDCA. Leha ho le joalo, lipatlisiso tse batsi ka batho li ntse li tsoela pele.
Na ursodiol e ka thusa sebete se mafura?
UDCA e molemo sebeteng se mafura. Leha ho le joalo, liteko tse entsoeng ka hloko li ntse li tsoela pele bakeng sa sehlooho se tšoanang.
Na ursodiol e fokotsa triglycerides?
UDCA e fumanoe e theola Low-density lipoproteins (LDL) le Very Low-Density Lipoproteins (VLDL). Leha ho le joalo, tekanyo ea kakaretso ea triglyceride ha e na liphetoho tse kholo ka mor'a phekolo ka phofo ea UDCA.
Na ho na le mokhoa o mong oa ursodiol?
Ho na le mokhoa o mong oa phekolo ho UDCA. Leha ho le joalo, katleho le katleho ea baemeli bao e bile phehisano. Ho buisana le ngaka mabapi le mokhoa oa ho atamela le hore na ke eng e molemohali ho uena ho ka u thusa.
Na ursocol ke lithibela-mafu?
Che, ursocol ha se lithibela-mafu. Ke lithethefatsi tse nang le mesebetsi e sa tšoaneng empa haholo-holo li sireletsa li-hepatocyte le ho thusa ho senyeha ha li-gallstones.
Na cholestasis ke lefu la sebete?
Cholestasis e bolela feela hore bile e emisa ho phalla haufi le sefate sa biliary kapa ho phalla hoa lieha. Tšitiso ena ea ho phalla ha bile e ka baka kotsi ea sebete le maloetse.
Ursodeoxycholic acid e sebetsa hakae?
UDCA e sebetsa hantle kalafong ea mafu a fapaneng a lefu la sebete hammoho le maemo a mang.
Ursodiol ke lithethefatsi tsa mofuta ofe?
UDCA ke bile acid ea bobeli. E bohlokoa haholo ho sireletsa kotsi ea cholangiocyte khahlano le litlamorao tse chefo tsa li-acid tsa bile, ho hlohlelletsa secretion ea biliary e senyehileng pele, ho hlohlelletsa ts'ebetsong ea detoxification khahlano le hydrophobic bile acids, kapa ho thibela apoptosis ke hore, ho shoa ha sele e ikemetseng ea hepatocyte.
Na ursodiol e theola k'holeseterole?
Liphuputso li bontša hore phofo ea Ursodeoxycholic acid e ka fokotsa maemo a k'holeseterole.
Na ursodiol e ka baka pancreatitis?
Pancreatitis ka tšebeliso ea UDCA ha e tloaelehe. UDCA e sebelisitsoe ho phekola pancreatitis.
Na ursodiol e etsa hore u otsele?
Mokhathala le bofokoli ke tse ling tsa litla-morao tse sa tloaelehang tsa UDCA.
References
- Tšebeliso ea ursodeoxycholic acid ho mafu a sebete. D Kumar, RK Tandon.J Gastroenterol Hepatol. 2001 Jan;16(1):3-14. doi: 10.1046/j.1440-1746.2001.02376.x.PMID: 11206313
- Ursodeoxycholic acid ka lefu la sebete sa cholestatic: mekhoa ea ts'ebetso le tšebeliso ea phekolo e tsosolositsoeng.Gustav Paumgartner , Ulrich Beuers.PMID: 12198643 DOI: 10.1053/jhep.2002.36088 Hepatology. 2002 Sep;36(3):525-31.
- Mekhoa ea ts'ebetso le ts'ebetso ea phekolo ea ursodeoxycholic acid ka lefu la sebete sa cholestatic.Gustav Paumgartner, Ulrich Beuers.PMID: 15062194 DOI: 10.1016 / S1089-3261 (03) 00135-1. 2004 Feb;8(1):67-81, vi.
- Kakaretso ea Pontšo ea Li-Bile Acids le Pono ea Pontšo ea Ursodeoxycholic Acid, The Most Hydrophilic Bile Acid, ka Pelong.Noorul Izzati Hanafi, Anis Syamimi Mohamed, Siti Hamimah Sheikh Abdul Kadir, Mohd Hafiz Dzarfan Othman.PMID: 30486474 PMCID: 6316857 PMCID Tlhaloso: 10.3390/biom8040159 Biomolecules. 2018 Nov 27;8(4):159.
- Ursodeoxycholic Acid Response Is Associated With Reduced Mortality in Primary Biliary Cholangitis With Compensated Cirrhosis.Binu V John, Nidah S Khakoo, Kaley B Schwartz, Gabriella Aitchenson, Cynthia Levy, Bassam Dahman, Yangyang Deng, David S Goldberg Kaplan Martin, David S Goldberg, Paul Martin , Tamar H Taddei.PMID: 33989225 PMCID: PMC8410631 (e fumaneha ka 2022-09-01) DOI: 10.14309/ajg.0000000000001280 Am J Gastroenterol. 2021 Sep 1;116(9):1913-1923.
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