NADH 2Na (606-68-8)

March 15, 2020

NADH ke mofuta oa enzyme ea nicotinamide adenine dinucleotide (NAD), mofuta o sebetsang oa coenzyme oa motsoako le vithamine B3 ……….

 


Boemo: Ka Phatlalatso ea Mesebetsi
E hlophisitsoeng le e rarahaneng e fumaneha
Bokhoni: 1277kg / khoeli

Video ea NADH 2Na (606-68-8)

Tlhaloso ea Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na) Litlhaloso

Name Product Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na)
Lebitso la lik'hemik'hale NADH (letsoai la disodium); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium letsoai; Nicotinamide adenine dinucleotide, e fokotsehile;
Nomoro ea CAS 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L.
Smile C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Molecular Formula C21H27N7Na2O14P2
Boima ba 'mele 709.4
Masapo a monoisotopic 709.088661 g / mol
Melting Point 140-142 ° C
Color Yellow
Stempage temp 2-8 ° C
Solubility H2O: 50 mg / mL, e hlakile ho fihlela e hlakile
kopo Bongaka; Lijo le phepo e nepahetseng;

 

Beta-Nicotinamide adenine dinucleotide disodium letsoai ke eng (NADH 2Na)?

NADH ke mofuta oa enzyme ea nicotinamide adenine dinucleotide (NAD), mofuta o sebetsang oa coenzyme oa motsoako le vithamine B3. NADH (b-Nicotinamide adenine dinucleotide) Letsoai la Disodium, le fokotsehileng, le tsejoang hape e le Nicotinamide adenine dinucleotide, ke coenzyme liphetohong tsa redox. Mesebetsi ea eona e le nchafatso ea mofani oa elektronike lits'ebetsong tse kenyelletsang glycolysis, β-oxidation le potric acid acid (potre ea Krebs, potoloho ea TCA). Letsoai la NADH disodium le boetse le nka karolo liketsahalong tsa ho tšoaea lisele, mohlala e le substrate ea poly (ADP-ribose) polymerases (PARPs) nakong ea karabelo ea tšenyo ea DNA. Joaloka letsoai le nang le disodium ea NADH, e sebelisoa lijong le phepelong ea phepo ho phekoleng lefu la Parkinson, lefu la mokhathala o sa foleng, lefu la Alzheimer's le mafu a pelo

 

Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na) melemo

Joaloka coenzyme ea oxidoreductase, letsoai la NADH disodium le bapala karolo ea bohlokoa tlhahisong ea matla a 'mele.

NADH disodium letsoai e ka lebisa ho hlaka kelellong, ho falimeha, ho tsepamisa mohopolo le ho hopola. E ka eketsa bohale ba kelello mme ea eketsa maikutlo. E ka eketsa maemo a matla 'meleng le ho ntlafatsa metabolism, matla a boko le mamello.

- Thusa batho ba nang le khatello ea maikutlo ea kliniki, khatello e phahameng ea mali kapa k'holeseterole e phahameng;

- Ntlafatsa ts'ebetso ea baatlelete;

Ho liehisa botsofali le ho boloka bots'epehi ba lisele tsa methapo ho ts'ehetsa sistimi ea methapo.

- A ka phekola lefu la Parkinson, a ntlafatsa ts'ebetso ea methapo ea kutlo bokong ba bakuli ba nang le lefu la Parkinson, a fokotsa bokooa ba mmele le litlhoko tsa lithethefatsi;

- Phekola lefu la mokhathala o sa foleng (CFS), lefu la Alzheimer le lefu la pelo;

- Sireletsa khahlanong le litla-morao tsa sethethefatsi sa AIDS se bitsoang zidovudine (AZT);

- Hanyetsa litlamorao tsa joala sebeteng;

- Mokhathala oa sefofane

 

Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na) litlamorao:

Hona joale, letsoai la NADH disodium le bonahala le sireletsehile ho batho ba bangata ha le sebelisoa ka nepo le ka nako e khuts'oane, ho fihlela libeke tse 12. Batho ba bangata ha ba na litla-morao ha ba nka chelete e khothalelitsoeng letsatsi ka leng, e leng 10 mg.

Leha ho le joalo, ha ho na datha tse lekaneng mabapi le ts'ebeliso ea letsoai la NADH disodium nakong ea bokhachane le nakong ea kanyeso. Ka hona ba lokela ho lula ka lehlakoreng le sireletsehileng le ho qoba tšebeliso.

 

Tlhaloso:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - mokhoa o mocha oa kalafo oa lefu la Parkinson. Papiso ea kopo ea molomo le ea botsoali. Acta Neurol Scand Suppl 1993; 146: 32-5 (Khatisitsoeng)
  • Budavari S, e hlophisitsoeng. Lenane la Merck. 12th ed. Setsi sa Whitehouse, NJ: Merck & Co., Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Molomo o fokotsoang oa B-nicotinamide adenine dinucleotide (NADH) o ama khatello ea mali, lipid peroxidation, le profid ea lipid ho likhoto tsa hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Molomo o fokotsoang oa B-nicotinamide adenine dinucleotide (NADH) o ama khatello ea mali, lipid peroxidation, le profid ea lipid ho likhoto tsa hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Na tlatsetso ea molomo ea coenzyme Q10 le NADH e ntlafatsa mofuthu le litekanyetso tsa biochemical ho syndrome ea mokhathala o sa feleng? Antioxid Redox Signal 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Kalafo ea lefu la Parkinson le NADH. Acta Neurol Scand 1994; 90: 345-7.