NADH 2Na (606-68-8)

March 15, 2020
SKU: 129311-55-3

NADH ke mofuta oa enzyme ea nicotinamide adenine dinucleotide (NAD), sebopeho se sebetsang sa coenzyme ea komporo le vithamine B3 ……….


Boemo: Ka Phatlalatso ea Mesebetsi
E hlophisitsoeng le e rarahaneng e fumaneha
Bokhoni: 1277kg / khoeli

Video ea NADH 2Na (606-68-8)

Tlhaloso ea Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na) Litlhaloso

Name Product Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na)
Lebitso la lik'hemik'hale NADH (letsoai la disodium); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium letsoai; Nicotinamide adenine dinucleotide, e fokotsehile;
Nomoro ea CAS 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
Smile C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Molecular Formula C21H27N7Na2O14P2
Boima ba 'mele 709.4
Masapo a monoisotopic 709.088661 g / mol
Melting Point 140-142 ° C
Color Yellow
Stempage temp 2-8 ° C
Solubility H2O: 50 mg / mL, e hlakile ho fihlela e hlakile
kopo Bongaka; Lijo le phepo e nepahetseng;

Beta-Nicotinamide adenine dinucleotide disodium letsoai ke eng (NADH 2Na)?

NADH ke mofuta oa enzyme ea nicotinamide adenine dinucleotide (NAD), e leng sebopeho se sebetsang sa coenzyme ea komporo le vithamine B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium letsoai, e fokotsehileng, hape e tsejoang e le Nicotinamide adenine dinucleotide, ke coenzyme maemong a redox. Mesebetsi ea eona e fana ka monehelo oa elektronike o ntlafatsang lits'ebetsong tsa catabolic ho kenyelletsa glycolysis, β-oxidation le potric acidjikele (potoloho ea Krebs, TCA). NADH disodium letsoai le eona e nka karolo liketsahalong tse tšoaeang lisele, mohlala joalo ka karoloana ea li-polymerase tsa polyP (ADP-ribose) (PARPs) nakong ea karabelo ea senya ea DNA. Joaloka letsoai la disodium ea NADH, e sebelisoa lijong le phepo e nepahetseng kalafong ea lefu la Parkinson, syndrome ea mokhathala o sa foleng, lefu la Alzheimer le mafu a pelo.

Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na) melemo

Ha e le coenzyme ea li-oxidoreductases, letsoai la NADH disodium le bapala karolo ea bohlokoa tlhahiso ea matla a 'mele.

- NADH disodium letsoai le ka lebisa ho hlaka hoa kelello, ho falimeha, ho tsepamisa mohopolo le ho hopola. E kanna ea eketsa ho fokola kelellong mme e ka eketsa molumo. E ka eketsa maemo a matla 'meleng' me ea ntlafatsa metabolism, matla a kelello le mamello.

- Thusa batho ba nang le khatello ea maikutlo tleliniking, khatello e phahameng ea mali kapa cholesterol e phahameng;

- Ntlafatsa ts'ebetso ea baatlelete;

- Ho lieha ho tsofala le ho boloka botsitso ba lisele tsa methapo ho ts'ehetsa ts'ebetso ea methapo;

- E kanna ea phekola lefu la Parkinson, e ntlafatsa ts'ebetso ea li-neurotransmitters bokong ba bakuli ba nang le lefu la Parkinson, fokotsa ho holofala 'meleng le litlhoko tsa lithethefatsi;

- Kalafo e sa foleng ea mokhathala o sa feleng (CFS), lefu la Alzheimer's le lefu la pelo;

- Sireletsa khahlanong le litlamorao tsa lithethefatsi tsa AIDS tse bitsoang zidovudine (AZT);

- Hanyetsa litlamorao tsa joala ho sebete;

- Mokhathala oa sefofane

Beta-Nicotinamide adenine dinucleotide disodium letsoai (NADH 2Na) litlamorao:

Hona joale, letsoai la NADH disodium le bonahala le sireletsehile ho batho ba bangata ha le sebelisoa ka nepo le ka nako e khuts'oane, ho fihlela libeke tse 12. Batho ba bangata ha ba na litla-morao ha ba nka chelete e khothalelitsoeng letsatsi ka leng, e leng 10 mg.

Leha ho le joalo, ha ho na datha tse lekaneng mabapi le ts'ebeliso ea letsoai la NADH disodium nakong ea bokhachane le nakong ea kanyeso. Ka hona ba lokela ho lula ka lehlakoreng le sireletsehileng le ho qoba tšebeliso.

Tlhaloso:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - mokhoa o mocha oa kalafo ho lefu la Parkinson. Papiso ea ts'ebeliso ea molomo le ea botsoali. Acta Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, ed. Lenane la Merck. 12th ed. Whitehouse Station, NJ: Merck & Co, Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Molomo o fokotsoang oa B-nicotinamide adenine dinucleotide (NADH) o ama khatello ea mali, lipid peroxidation, le profid ea lipid ho likhoto tsa hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Molomo o fokotsoang oa B-nicotinamide adenine dinucleotide (NADH) o ama khatello ea mali, lipid peroxidation, le profid ea lipid ho likhoto tsa hypertensive (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Na tlatsetso ea molomo ea coenzyme Q10 le NADH e ntlafatsa mofuthu le litekanyetso tsa biochemical ho syndrome ea mokhathala o sa feleng? Antioxid Redox Signal 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Phekolo ea lefu la Parkinson le NADH. Acta Neurol Scand 1994; 90: 345-7.