Video ea Raw Compound 7P (1890208-58-8) video
Sekhahla sa Raw 7P phofo (1890208-58-8) Tlhaloso
Pherese e Meholo ea 7P e khothalletsang ho fela ha neurite ea li-neurone tsa mantlha tse meholo tse tsoang ho hippocampus, cerebral cortex le retina. ka mohlala oa liphoofolo oa maqeba a methapo ea optic, phofo ea Raw Compound 7P e ile ea bontšoa ho etsa hore ho be le li-axone tse ntle tsa 43, e leng se bontšang hore phofshoana ea mahlaseli a Raw Compound 7P e fetoha phetoho ea ho tsosolosoa ha axon ka vivo.further optimization of Metsoako a mahlaseli a 7P le ho hlakisoa ha mekhoa eo e etsang hore ho tsosolosoa ha axone ho eona e tla fana ka motheo o utloahalang oa boiteko ba nakong e tlang ea ho ntlafatsa maano a phekolo.
Raw 2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide (Compound 7P) phofo (1890208-58-8) Slitšobotsi
| Name Product | 2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide (Raw Compound 7P powder) |
| Lebitso la lik'hemik'hale | 2 - ((2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide (Raw Compound 7P phofo) |
| Brand Name | Pherese e meholo 7P phofo |
| Sehlopha sa Lithethefatsi | Lithethefatsi tsa Nootropic |
| Nomoro ea CAS | 1890208-58-8 |
| InChIKey | NAXWKPFXCOBXLE-UHFFFAOYSA-N |
| limolek'hule Formula | C22H23N3O5S |
| limolek'hule Wtse robeli | 441.508g |
| Masapo a monoisotopic | 440g / mol |
| Ntlha e qhibilihisang | N / A |
| Fho tsosolosa Poli | N / A |
| Likokoana-hloko tsa Half-Life | N / A |
| Color | Pula e tšoeu |
| Sho khoneha | ho itšilafatsa ka metsing le ka ethanol. |
| Storage Tmocheso | Boloka mocheso oa kamoreng, ka setsing se tiisitsoeng, qoba mocheso o matla le leseli. |
| Aho latela | • Ho eketsa ts'ebetsong • Ho ntlafatsa maikutlo • Thusa ho loantša mokhathala • E thibela lisebelisuoa ka hare ho boko • Tšoara kotsi e amanang le joala |
Raw 7P e kopaneng phofo (1890208-58-8) Tlhaloso
Raw Compound 7P (2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide) phofo e khothalletsang lekhalo la methapo ea methapo ea methapo e tsoang ho hippocampus , bokong bokong, le retina. ka mohlala oa phoofolo oa kotsi ea optic methapo, Raw Compound 7P phofo e ile ea bontšoa ho hlohlelletsa kholo ea li-axon tse ntle tsa 43, e bontšang hore in vitro neurite outgrowth activity ea Raw Compound 7P powder e fetolela ts'usumetso ea nchafatso ea axon ka vivo. Raw Compound 7P phofo le ho hlakisoa ha mekhoa eo e hlahisang nchafatso ea axon ka vivo e tla fana ka motheo o utloahalang oa boiteko ba kamoso ba ho ntlafatsa maano a kalafo.
Tšebeliso ea Compilation 7P phofo (1890208-58-8)
Palo ea 7p (2 - [(2-methoxyphenyl) [(4-methyl phenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide) e bontšitse mosebetsi o phahameng ka ho fetisisa khahlanong le lisele tsa kankere ea kokoana-hloko. Ka mouse e nude xenograft mohlala e kenngoa ka lisele tsa HeLa, 7p e ne e bontša ho thibela ho lemalla ha kankere ea malapa. Tlhahlobo ea hae ea litsebi tsa mahlaseli a nang le lik'hemik'hale a bontšang hore 7p e ntlafalitse microstructure ka mokhoa o itšetlehileng ka tekanyo ea methapo. 7p e nang le likarolo e boetse e ekelitse boholo ba lisele tsa HeLa ho G0 / G1 le S-phase mme e fokotseha haholo ka karolo ea karolo ea G2 / M. Litholoana tsa 7p ho C-caspase-3, C-caspase-9, Bcl-2 le polelo ea Bax ho HeLa lisele li ne li boetse li ikemiselitse.
Tlhahlobo ea tubulin polymerization, lithuto tsa immunofluorescence, tlhahlobo ea li-cell cycle le tlhōlisano ea tubulin-binding assay e bontšitse ka matla hore 7p ke colchicine e tlamang sebaka sa inhibitor ea tubulin.
melemo e of 7P e kopaneng phofo (1890208-58-8)
7p e khothalletsang ho tsosolosoa ha optic e pshatlehileng
Lokisa tšenyo ea hlooho ea hlooho
Recommended 7P e kopaneng phofo (1890208-58-8) Tekanyo
7p e hlahisitse 100% ho thibela likokoana-hloko ka letsatsi 4 ka tekanyo e mengata (100, 50, le 25 mg / kg) e fanoang ka matsatsi a mane a latellanang, empa ka 100 mg / kg, litoeba tsohle li ile tsa pholoha 'me tsa phekoloa, ha 50 mg / kg, litoeba tse tharo ho tse hlano li ile tsa pholoha 'me litoeba tse peli tsa phekoloa,' me ka 25 mg / kg, ha ho le e 'ngoe ea litoeba tse ileng tsa pholoha
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