Pyrroloquinoline quinone disodium letsoai (122628-50-6)

March 16, 2020

PQQ ke mofuta o mocha oa livithamini tse qhibilihang ka har'a metsi, o fumanoeng ka lekhetlo la pele e le sebapali sa …….

 


Boemo: Ka Phatlalatso ea Mesebetsi
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Pyrroloquinoline quinone disodium letsoai (122628-50-6) video

Tlhaloso ea Pyrroloquinoline quinone disodium letsoai (122628-50-6) Litlhaloso

Name Product Pyrroloquinoline quinone disodium letsoai (122628-50-6)
Lebitso la lik'hemik'hale Pyrroloquinoline quinone letsoai la sodium; disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo (2,3-f) quinoline-2,7,9-tricarboxylat; PQQ, Pyrrolo-quinoline-quinone disodium letsoai; sodiuM 9-carboxy-4,5 -dioxo-4,5-dihydro-1H-pyrrolo [2,3-f] quinoline-2,7-dicarboxylate; PQQ disodium
Nomoro ea CAS 122628-50-6
InChIKey UFVBOGYDCJNLPM-UHFFFAOYSA-L
Smile C1=C(C2=C(C(=O)C(=O)C3=C2NC(=C3)C(=O)O)N=C1C(=O)[O-])C(=O)[O-].[Na+].[Na+]
Molecular Formula C14H4N2Na2O8
Boima ba 'mele 374.17
Masapo a monoisotopic 373.976304 g / mol
Melting Point > 300 ℃ (e bole nakong ea tlhahlobo)
Color 'Mala o bofubelu bo bofubelu ho Reddish Brown Fine Powder
Setsi sa polokelo 2-8 ° C
Solubility Ho qhibiliha ka metsing
kopo Ho etsoa tlhahiso ea letsoai la pyrroloquinoline quinone (PQQ) ka lebaka la boleng ba eona bo botle United States (US) lijong, tse kang matla, lipapali le lino tsa isotonic; lino tse nooang tse seng lebese; metsi (a khabisitsoe, a ntlafalitsoe, a matlafalitsoe); lino tse tlotsitsoeng ka lijo tsa lebese; mekoallo ea lijo-thollo le granola; le matla, phetisetso ea lijo, le mekoallo e sirelelitsoeng.

 

Pyrroloquinoline quinone disodium letsoai ke eng (PQQ disodium letsoai)?

PQQ ke mofuta o mocha oa livithamini tse qhibilihang ka metsing, li qalile ho fumanoa e le cofactor bakeng sa karabelo ea enzyme ho libaktheria, moo e sebetsang ka mokhoa o ts'oanang le oa livithamini tsa B ho batho. Ke oxidoreductase-based, e teng linthong tse ling tse nyane, limela le lisele tsa liphoofolo, ha e amehe feela ho matlafatseng oxidation ea karabelo ea 'mele, empa hape e na le ts'ebetso e ikhethang ea biological le ts'ebetso ea' mele. Letšoao la PQQ le ka ntlafatsa metabolism ea lisele tsa tlhaho le kholo ea ts'ebetso, e bohlokoa haholo.

 

Pyr e joang?Roloquinoline quinone disodium letsoai sebetsa?

Pyrroloquinoline quinone disodium letsoai le ka kenyelletsa ketso e tobileng ho li-enzyme tsa bohlokoa tse kenyelletsoeng ho matla a hlahisang matla ka har'a lisele tsa rona - mitochondria, theapy e ntlafatsa tlhahiso ea matla. Pyrroloquinoline quinone disodium letsoai Ntle le ho ba le phello e matla ea antioxidant, e ka boela ea sireletsa khahlanong le tšenyo ea mitochondrial. Ha e sireletse li-mitochondria feela ho tsoa likhatellong tsa oxidative, e boetse e phahamisa moloko o ikhethileng oa mitochondria e ncha ka har'a lisele tse tsofetseng.

Melemo ea letsoai la Pyrroloquinoline quinone disodium

Pyrroloquinoline quinone disodium letsoai ke motsoako oa tlhaho o seng o ntse o le teng liseleng tsa rona, o na le melemo e metle ho batho:

- Thusa ho ntlafatsa tšebetso ea 'mele ea ho itšireletsa mafung le e phahameng;

Thibela le ho phekola tšenyo ea sebete;

Fokotsa tšenyo e kholo ea 'mele oa motho;

Laola maloetse a fapaneng a methapo;

- Romote absorption ea amino acid;

Thibela le ho phekola lefu la alzheimer;

- Lisele tsa NK tse sebetsang, li ntlafatsa ts'ebetso ea li-antitumor;

- Ho ntlafatsa boleng ba boroko le bolelele ba nako hammoho le metriki e meng ho latela boroko bo ntlafalitsoeng;

- Ho eketsa lintlha tsa sengoloa tse sebelisang li-antioxidant pathways;

- E ntlafatsa ho theoa ha mitochondria e ncha mme e eketsa tlhahiso ea matla a sele.

 

Kopo ea Pyrroloquinoline quinone disodium letsoai

Pyrroloquinoline quinone disodium letsoai ke letsoai la disodium ea Pyrroloquinoline quinone, ts'ebetso ea eona e ts'oana le Pyrroloquinoline quinone.

Phuputsong ea 2009 e phatlalalitsoeng koranteng ea bongaka ea Lijo ka mokhoa oa Lijo, Pyrroloquinoline Quinone o bontšitsoe a na le bokhoni ba ho thusa ho sireletsa. E sebelisoa ho sireletsa ho theoha ha kelello (ho lahleheloa ke mohopolo, ho thatafalloa ke ho ithuta, joalo-joalo) ka lebaka la botsofali, ho otloa kapa lefu la methapo ea kutlo, le tšireletso liketsahalong tsa pelo le methapo ea mokokotlo. Liphetho tse tšoanang li tlalehiloe tlhahlobong ea morao-rao ea 2011 moo Pyrroloquinoline Quinone le eona e fanoeng ka kotloloho e le tlatsetso ea lijo, joalo ka lino tse tahang tse entsoeng ka lebese.

 

Tlhaloso:

[1] Nakano M, Takahashi H, Koura S, Chung C, Tafazoli S, Roberts A. Acute le subchronic toxicity lithuto tsa pyrroloquinoline quinone (PQQ) disodium letsoai (BioPQQ ™) litekong. Regul Toxicol Pharmacol. 2014 Oct; 70 (1): 107-21. Doi: 10.1016 / j.yrtph.2014.06.024. Epub 2014 Jul 1. PMID: 24995591.

[2] Itoh Y, Hine K, Miura H, Uetake T, Nakano M, Takemura N, Sakatani K. Phello ea Antioxidant Supplement Pyrroloquinoline Quinone Disodium letsoai (BioPQQ ™) mabapi le Mesebetsi ea Kelello. Adv Exp Med Biol. 2016; 876: 319-325. Doi: 10.1007 / 978-1-4939-3023-4_40. PMID: 26782228.

[3] Nakano M, Kawasaki Y, Suzuki N, Takara T. Liphetoho tsa Pyrroloquinoline Quinone Disodium Cake Bath on the Serum Cholesterol Levels of Healthy Japan Adults. J Nutr Sci Vitaminol (Tokyo). 2015; 61 (3): 233-40. doi: 10.3177 / jnsv.61.233. PMID: 26226960.

[4] Rucker R, Chowanadisai W, Nakano M. Bohlokoa ba 'mele bo amanang le quinone ea pyrroloquinoline. Altern Med Rev. (2009)

[5] Noji N, et al. Mokhoa o bonolo le o hlokolosi oa tlhahlobo ea pyrroloquinoline quinone (PQQ) lijong tse fapaneng tse sebelisang metsi chromatography / electrospray-ionization tandem mass spectrometry. J Agric Chem Chem. (2007)