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Lithium orotate (5266-20-6)

Lithium orotate ke letsoai le nang le lithium (tšepe ea alkali) le orotic acid (e hlahisoang ka tlhaho 'meleng) …….


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E hlophisitsoeng le e rarahaneng e fumaneha
Bokhoni: 1277kg / khoeli

Tlhaloso

Lithium orotate (5266-20-6) songolo

Name Product Lithium orotate
Lebitso la lik'hemik'hale orotic acid lithium letsoai monohydrate ; lithium; 2,4-dioxo-1H-pyrimidine-6-carboxylate; Lithiiorotasmonohydricum; UNII-L2N7Z24B30;
Nomoro ea CAS 5266-20-6
InChIKey IZJGDPULXXNWJP-UHFFFAOYSA-M
Smile [Li +]. C1 = C (NC (= O) NC1 = O) C (= O) [O-]
Molecular Formula C5H5LiN2O5
Boima ba 'mele 180.04
Masapo a monoisotopic 162.025285 g / mol
Melting Point ≥300 ° C
Boiling Point N / A
Color o mosoeu
kopo ver-the-counter lithium orotate e khothalletsoa e le tlatsetso ea bophelo bo botle bakeng sa tšebeliso e le mohloli o tlase oa lethal; e ka sebelisoa bakeng sa lethathamo le tlase la lithium orotate kalafong ea joala, migraines, le khatello ea maikutlo e amanang le lefu la ho ferekanya kelello.

Lithium orotate ke eng?

Lithium orotate ke letsoai le nang le lithium (tšepe ea alkali) le orotic acid (e leng motsoako o hlahisoang ka tlhaho 'meleng). Ka har'a komporo ena, lithium ha e kopane ka kotloloho le ion ea orotate, ho e-na le carbonate kapa ion e 'ngoe, joalo ka letsoai le leng, e ikarola ka tharollo ea ho hlahisa li-lithium tsa ion. Bongata ba lithium orotate e fumanehang khoebong e fanoa ka mokhoa oa litlatsetso tsa phepo, e fanoa e le kalafo ea tlhaho bakeng sa mathata a fapaneng a bophelo bo botle ba kelello, leha ho le joalo, ho sa tsoa etsoa lipatlisiso bohareng ba 1973-1986 ho phekola maemo a itseng a bongaka, joalo ka bokhoba ba tahi le lefu la Alzheimer's. .

Joaloka mofuta o mong oa kalafo, lithium orotate e ka nkela lithium 'me ea sebelisoa ho phekola le ho thibela manonyeletso a batho ba nang le lefu la ho ferekana kelellong. Lithium ho thoe e phekola le ho thibela manonyeletso a manonyeletso ka ho fokotsa ts'ebetso e sa sebetseng ea boko.

Le ha ka linako tse ling acid e orotic e bitsoa Vitamin B13, ha e hlile ha e nkuoe e le vithamine. 'Meleng oa motho, asiti ea orotic e ka hlahisoa ho tsoa ho likokoana-hloko tse fumanehang ka mala. Ntle le moo, e na le lisebelisoa tse ling tse ntle bokong le 'meleng.

Lithium orotate e sebetsa joang?

Letswai la lithium la orotic acid (lithium orotate) le ntlafatsa litlamorao tse ikhethileng tsa lithium-makhetlo a mangata ka ho eketsa ts'ebeliso ea lithium bio. Li-orotates li tsamaisa lithium ho li-membran tsa mitochondria, lysosomes le lisele tsa glia. Lithium orotate e tsitsisa membrous ea lysosomal mme e thibela karabelo ea enzyme e ikarabellang bakeng sa ho theoha ha sodium le litlamorao tsa ho omella hoa letsoai le leng la lithium.

Melemo ea Lithium orotate

Lithium orotate e sebelisetsoa ho phekola mania kapa khatello ea maikutlo ho bakuli ba nang le lefu la ho ferekana kelellong le ho thibela ho phetoa ha manonyeletso. E ka boela ea thusa ba nang le matšoenyeho a tebileng a tsoang ho PTSD mme e ka thusa e le ho thefula mohopolo bakeng sa tlhaselo ea letsoalo.

Bohareng ba lilemo tsa bo-80 ho ile ha etsoa lipatlisiso tsa joala 'me tsa fumana hore kalafo ea Lithium orotate letsatsi le leng le le leng e thusa lino tse tahang leetong la bona ho tlohela ho noa. Ba nang le bothata ba OCD le ho se bone hantle ba ka rua molemo ho eona. Ho feta moo, Lithium orotate ha e sebelise feela kalafo ea tlhabollo, empa hape e ka thusa ho sebetsana le nako ea ts'ebetso ea ntlafatso.

Hape, Lithium orotate e boetse e bapala karolo e ntle ho sireletseng bokong. Lithium orotate e sireletsa boko ka ho thibela tahlehelo ea lisele tsa boko le ho hlahisa lisele tse ncha tsa boko. E bontšitse ho khutlisa boemo ba Parkinson, lefu la Alzheimer's le 'dementia'. Boithuto ba liphoofolo bo ile ba bonts'a ntlafatso ea likotsi tsa methapo ea mokokotlo le likotsi. Ho ka boela ha e-ba molemo joalo ka tšireletso ts'ebetsong ea methapo ea methapo ka lebaka la lefu la Lyme hape e ka u sirelletsa ho "brain shrinkage"

Litekanyetso tsa "lithium orotate"

Ka lebaka la phapang e phahameng ea bioavailil ea lithium orotate, litekanyetso tsa kalafo li tlase haholo ho feta mefuta e fanoang ke lithium. Ho na le le melemo e mengata ea ho nka lithium orotate ka litekanyetso tse tlase.

Tekanyetso e tloaelehileng e pakeng tsa hlano le 20 mg. Ba ka e fana ka mofuta oa metsi, hangata ho pota 250mcg. Ka tekanyetso ena, ha e chefo.

Maemong a khatello ea maikutlo e matla, kalafo ea kalafo ea lithium orotate ke 150 mg / letsatsi. Sena se bapisoa le 900-1800 mg ea liforomo tsa ngaka. Lenaneng lena la litekanyetso tsa lithium orotate, ha ho na mefuta e fapaneng ea ho amohela litumelo mme ha ho na tlhoko ea ho lekanya litekanyo tsa serum ea mali.

Tšebeliso ea Lithium orotate / lits'ebetso

E le tlatsetso ea lijo, Lithium orotate e ka sebelisoa ka tekanyetso e nyane ho phekola maemo a kang khatello ea maikutlo, bokhoba ba tahi, ADHD le ADD, khatello ea maikutlo, khatello ea maikutlo, PTSD, Lefu la Alzheimer's le taolo ea khatello ea maikutlo ka kakaretso.

Ka litlhare tse ling, lithium orotate e ka sebelisoa ho phekola le ho thibela maemo a latelang:

ho Tšoenyeha

Lefu la ho ferekana kelellong

Hlooho ea hlooho ea Cluster

ho tepella maikutlo

Glaucoma

lefu la ho hlobaela

Migraine

Lefu la Parkinson

Bothata ba ho imeloa ke khatello ka morao

Ho feta moo, lithium orotate e boetse e sebelisetsoa ho ntlafatsa mohopolo, ho kokobetsa bohloko le ho fokotsa khatello ea maikutlo.

Lithium orotate litla-morao

Ntle le melemo e kaholimo, lithium orotate e boetse e baka litlamorao ho 'mele, joalo ka beow:

Tlaleho ea 2007 e phatlalalitsoeng ho Journal of Medical Toxicology e lemosa hore lithium orotate e ka ba le litlamorao tse mpe, tšebeliso e sa feleng ea lithium orotate e ka baka ho nyekeloa le letsoalo. Hammoho le ho nyekeloa le pelo le ho hlatsa, e boetse e baka mathata a pelo le mathata a methapo ea kutlo. Ho boetse ho na le ts'oaetso ea hore ts'ebeliso ea lithium orotate e ka fokotsa ts'ebetso ea liphio.

Hape, lithium orotate e ka ba le tšebelisano e itseng le meriana e meng. joalo ka li-inhibitors tsa ACE, li-anticonvulsants, li-antidepressants, calcium block blockers, dextromethorphan, loop diuretics, meperidine, methyldopa, le monoamine oxidase inhibitors (MAOIs), jj.

Ha o nahana ka likotsi tsa bophelo bo botle tse amanang le chefo ea thium, o hloka ho hlahlojoa khafetsa ho netefatsa hore lithethefatsi tse chefo ha li fihlelle ha u sebelisa lithium orotate.

Tlhaloso:

  • Komiti ea ACOG ea li-Bulletins tsa Li-Practice — Li-Obstetrics. Bulletin ea ACOG: Litataiso tsa taolo ea bongaka bakeng sa lingaka tsa basali tse thibelang mafutsana 'meleng ka karolo ea 92, Mphalane 2008 (li nka sebaka sa palo ea boikoetliso 87 Tšebeliso ea meriana ea mafu a kelello nakong ea bokhachane le pelehi. Obstet Gynecol. 2007; 2008: 111-1001.
  • Balon R. Kotsi e ka ba teng ea "phepo e nepahetseng" lithium orotate. Ann Clin Psychiatry. 2013; 25 (1): 71.23376874.
  • Barkins R. Low-lethal lithium le litlamorao tsa eona tsa ts'ehetso ea bophelo. Qeto ea Nutr. 2016; 39 (3): 32-34.
  • Heim W, Oelschläger H, Kreuter J, Müller-Oerlinghausen B. Ho lokolloa ha lithium ho tloha litokisetsong tse tsitsitseng tsa tokollo. Papiso ea lihlahisoa tse supileng tse ngolisitsoeng. Pharmacopsychiatry. 1994; 27 (1): 27-31.8159780.
  • Nieper, Hans Alfred (1973), "Lisebelisoa tsa bongaka tsa lithium orotate. Ho ithuta lilemo tse peli ”, Agressologie, 14 (6): 407–11, PMID 4607169.
  • Gong R, Wang P, Dworkin L. Seo re hlokang ho se tseba ka phello ea lithium maling. Am J Physiol Renal Physiol. 2016; 311 (6): F1168-F1171.27122541.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


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