Lactoferrin (146897-68-9) tsa video
Lactoferrin phofo Slitšobotsi
| Name Product | Lactoferrin |
| Lebitso la lik'hemik'hale | lactotransferrin (LTF) |
| Brand Name | N / A |
| Sehlopha sa Lithethefatsi | N / A |
| Nomoro ea CAS | 146897-68-9 |
| InChIKey | N / A |
| limolek'hule Formula | C141H224N46O29S3 |
| limolek'hule Wtse robeli | EA-87 kDa |
| Masapo a monoisotopic | N / A |
| Sebaka se belang | N / A |
| Fho tsosolosa Poli | N / A |
| Likokoana-hloko tsa Half-Life | N / A |
| Color | pinki |
| Sho khoneha | H2O: 1 mg / mL |
| Storage Tmocheso | 2-8 ° C |
| Aho latela | N / A |
ke eng Lactoferrin?
Lactoferrin (LF), e tsejoang hape e le lactotransferrin (LTF), ke glycoprotein e emeloang haholo metsing a fapaneng a sekhukhu a kenyelletsang lebese. CRM ena ea bolelele bo felletseng e loketse joalo ka lisebelisoa tsa ho qala ho sebelisoa ho li-calibrator kapa li-control bakeng sa likopo tse fapaneng tsa liteko tsa LC-MS / MS ho kenyelletsa tlhahlobo ea allergen, tlhahlobo ea lebese la masea, ts'ebeliso ea lijo kapa phepo e nepahetseng le tlhahlobo ea tlhahlobo ea mafu.
Colostrum, lebese la pele le hlahisoang ka mor'a hore ngoana a hlahe, le na le lactoferrin e phahameng, e batlang e le makhetlo a supileng a palo e fumanoang lebeseng e hlahisoang hamorao. Lactoferrin e boetse e fumanoa metsing a tsoang leieng, nko, phepaneng ea matšoafo, mala le libakeng tse ling. Batho ba sebelisa lactoferrin e le moriana.
Lactoferrin e sebelisetsoa ho phekola liso tsa ka mpeng le mala, lets'ollo, le hepatitis C. E boetse e sebelisoa e le antioxidant le ho itšireletsa khahlanong le tšoaetso ea baktheria le vaerase. Lisebelisoa tse ling li kenyelletsa ho matlafatsa tsamaiso ea 'mele ea ho itšireletsa mafung, ho thibela tšenyo ea lisele tse amanang le botsofali, ho khothaletsa libaktheria tse phetseng hantle tsa mala, ho thibela mofetše, le ho laola tsela eo' mele o sebetsanang le tšepe ka eona.
Bafuputsi ba bang ba re lactoferrin e ka bapala karolo ea ho rarolla mathata a bophelo bo botle ba lefats'e joalo ka khaello ea tšepe le lets'ollo le matla.
Temong ea indasteri, lactoferrin e sebelisetsoa ho bolaea libaktheria nakong ea ts'ebetso ea nama.
Lactoferrin ke karolo ea sesole sa 'mele ebile e na le ts'ebetso ea antimicrobial. Ntle le mesebetsi ea mantlha ea ho kopanya le ho tsamaisa tšepe, Lactoferrin e boetse e na le mesebetsi le litšoaneleho tsa tšepe e thibelang likokoana-hloko, antivirus, ho hanyetsa likokoana-hloko, catalysis, thibelo ea mofetše le ntoa khahlanong le mofetše, allergy le ts'ireletso ea mahlaseli. Batho ba bang ba nka lactoferrin tlatsana ho fumana melemo ea antioxidant le anti-inflammatory.
Melemo ea Lactoferrin
Liphetoho tse khahlanong le ho Ruruha
Le ha mochine o tobileng o e-so ka o theoa leha ho le joalo, lactoferrin ke karolo e tsebahalang ea anti-inflammatory ho batho.
Lactoferrin e mokelikeling oa amniotic ke karolo ea bohlokoa ea ho fokotsa ho ruruha ha lesea ho basali ba baimana ka ho fokotsa maemo a IL-6 le ho fokotsa tšoaetso e bakang ho ruruha.
E na le thepa e khahlanong le ho ruruha ha e sebelisana le sesole sa 'mele khahlanong le vaerase ea Epstein-Barr, e fokotsa ho ruruha ka ho thibela ts'ebetso ea TLR2 le TLR9 ho DNA ea vaerase.
Thepa ea antibacterial
Lactoferrin e thusa ho emisa tšebetso ea libaktheria. Libaktheria tse ngata li hloka tšepe hore e sebetse, 'me lactoferrin e ka emisa libaktheria ho nka tšepe' meleng oa motho.
Ntle le sena, e ka thibela metabolism ea lik'habohaedreite, ea ntlafatsa mabota a sele, kapa ea kenella le li-lysozymes ka lebese ho emisa libaktheria.
Likarolo ntlafatsong ea bokhachane / masea
Masea a hloka lactoferrin ho nts'etsapele le ho ikamahanya le tsamaiso ea mala. E na le boikarabello ba ho khetholla lisele tse nyane tsa mala a ka mpeng, e amang boima ba 'mele ba ka mpeng, bolelele le polelo ea enzyme.
Ho "fetus" ea motho, lactoferrin e sebetsa e le taolo ea kholo ea masapo mekhatlong ea pele ea kholo ea masapo a motho.
Lactoferrin e khothalletsa kholo ea lisele tsa cartilaginous maemong a fapaneng a kholo ea bokhachane ka ho susumetsa osteocytes le li-osteoblasts.
Lithabeng tsa batho, Lactoferrin e phahamisa ho kenngoa ha tšepe le nts'etsopele ea moeli oa brashi, e leng se lumellang ho hola hantle le nts'etsopele ea mala pele a hlaha.
Maemo a phahameng a Lactoferrin ka popelong a thibela tšoaetso le ho phatloha ha litho tsa ka popelong ha a ntse a eketsa monyetla oa ho pepa.
Lactoferrin e sebetsa joang?
Lactoferrin e thusa ho laola ho kenngoa ha tšepe ka mpeng le ho tsamaisa tšepe liseleng.
E boetse e bonahala e sireletsa khahlanong le tšoaetso ea baktheria, mohlomong ka ho thibela kholo ea libaktheria ka ho li amoha limatlafatsi tse bohlokoa kapa ka ho bolaea libaktheria ka ho senya mabota a sele ea tsona. Lactoferrin e fumanehang ka lebeseng la bo-mme e pakoa ka ho thusa ho sireletsa masea a anyesitsoeng khahlanong le tšoaetso ea baktheria.
Ntle le tšoaetso ea baktheria, lactoferrin e bonahala e sebetsa khahlano le tšoaetso e bakoang ke vaerase e meng le fungus.
Lactoferrin e boetse e bonahala e ameha ka taolo ea ts'ebetso ea marapo (myelopoiesis), 'me ho bonahala e khona ho matlafatsa ts'ireletso ea mmele ea ts'ireletso (immune system).
Litla-morao tsa Lactoferrin
Lactoferrin phofo e bolokehile ka bongata bo sebelisoang lijong. Ho ja lactoferrin e ngata ho tsoa lebeseng la khomo le hona ho ka bolokeha ho fihlela selemo. Lactoferrin ea motho e entsoeng ka raese e entsoeng ka ho khetheha e bonahala e bolokehile ho fihlela matsatsi a 14. Lactoferrin e ka baka lets'ollo. Ka tekanyetso e phahameng haholo, ho tlalehiloe letlalo, ho lahleheloa ke takatso ea lijo, mokhathala, ho hatsela le ho sokela.
Lactoferrin phofo sebelisa khanya le kopo
MILK E NANG LE MOTSOALLE
Ho masea a macha a boima bo tlase, lebese la masea le matlafalitsoeng ka lactoferrin (e nang le probiotic kapa e se nang) e fokotsa kotsi ea ho lieha ho qala ha septicemia (baktheria kapa fungal).
Tlhahlobo e tebileng ea sephetho e bonts'itse hore bovine lactoferrin e fokotsitse ts'oaetso ho e-na le ho thibela fungus ho ata. Sena se fana ka maikutlo a hore lactoferrin e khona ho thibela tšoaetso ea fungal hore e se ke ea fetoha lefu la systemic.
Bovine lactoferrin e ka mpefatsa tšitiso ea mali le bokong ka li-receptor tse itseng, le ho ntlafatsa neuroprotection, neurodevelopment le bokhoni ba ho ithuta ho limmong.
Reference:
- Barrington K et al, Teko ea Lacuna: teko ea sefofane e laoloang habeli e sa sebetseng e kopantseng tlatsetso ea lactoferrin ka lesea la pele ho pele, J Perinatol. 2016 Aug; 36 (8): 666-9.
- Lauterbach R et al., Lactoferrin - glycoprotein ea menyetla e meholo ea kalafo, Dev Period Med. 2016 Mphalane-Jun; 20 (2): 118-25.
- Nophaine e laoloang ke Nbr1 ho Lactoferrin-induction osteoblastic. Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM. Biosci Biotechnol Biochem. 2020 Mar
- Liphetho tsa Dose of Bovine Lactoferrin Forforation mabapi le Iron Metabolism of Anemic Infants. Chen K, Zhang G, Chen H, Cao Y, Dong X, Li H, Liu C. J Nutr Sci Vitaminol (Tokyo). 2020
- Lactoferrin: Sebapali sa Bohlokoa ho Ts'ireletso ea Neonatal. Telang S et al. Nutrients. (2018)
- Karolo ea Lactoferrin ho Neonates le masea: Tlhahlobo. Manzoni P et al. Ke J Perinatol. (2018)
- Tlatsetso ea ente ea lactoferrin bakeng sa thibelo ea sepsis le necrotizing enterocolitis ho masea a preterm. Pammi M et al. Cochrane Database Syst Rev. (2017)
- Melemo ea Lactoferrin ke Efe Molemong oa Batho ba baholo le masea?