Video ea Urolithin A （1143-70-0）
Urolithin A （1143-70-0）songolo
| Name Product | Urolithin A phofo |
| Lebitso la lik'hemik'hale | 3,8-dihydroxy-6H-benzo [c] chromen-6-e le 'ngoe;
3,8-Dihydroxy-6H-dibenzo (b, d) pyran-6-ngoe; 3,8-Dihydroxyurolithin; 3,8-dihydroxybenzo [c] chromen-6-ngoe; 6H-Dibenzo [b, d] pyran-6-ngoe, 3,8-dihydroxy-; 3,8-Hydroxydibenzo-alpha-pyrone; |
| Nomoro ea CAS | 1143-70-0 |
| InChIKey | RIUPDUFZCXCHM-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1O)C(=O)OC3=C2C=CC(=C3)O |
| limolek'hule Formula | C13H8O4 |
| limolek'hule Wtse robeli | 228.2 g / mol |
| Masapo a monoisotopic | 228.042259 g / mol |
| Ntlha e qhibilihisang | 340-345 ° C |
| Sebaka se belang | 527.9 ± 43.0 ° C (E boletsoe esale pele) |
| Flash point | 214.2ºC |
| Likokoana-hloko tsa Half-Life | Urolithin A e teng morotong ho fihlela lihora tse 48 kamora ts'ebeliso ea lero la kharenate. |
| Color | E tšoeu ho beige |
| Sho khoneha | DMSO: 20 mg / mL, hlakileng |
| Storage Tmocheso | 2-8 ° C |
| Aho latela | E sebelisoa e le tlatsetso ea lijo le sehlahisoa se khahlanong le botsofali, e ka sebelisoa ho fokotsa ho ruruha le ho loantša mofetše; |
Tlhaloso:
[1] Garcia-Munoz, Cristina; Vaillant, Fabrice (2014-12-02). "Phello ea Metabolic ea Ellagitannins: Litlamorao ho Bophelo bo Botle, le Lits'ebetso tsa Patlisiso bakeng sa Lijo Tse Sebetsang Tse Sebetsang". Litlhahlobo tse Bohlokoa ho Saense ea Lijo le Phepo e Ntle. 54 (12): 1584–1598. doi: 10.1080 / 10408398.2011.644643. ISSN 1040-8398. PMID 24580560. S2CID 5387712.
[2] Ryu, D. le al. Urolithin A e fokotsa mitophagy mme e lelefatsa bophelo ba motho ho C. elegans mme e eketsa ts'ebetso ea mesifa litoeba. Nat. Med. 22, 879-888 (2016).
[3] "Tsebiso ea FDA GRAS ea GRN ea 791: urolithin A". Tsamaiso ea Tsamaiso ea Lijo le Lithethefatsi ea US. La 20 Tšitoe 2018. E khutlisitsoe ka la 25 Phato 2020.
[4] Singh, A .; Andreux, P.; Blanco-Bose, W.; Ryu, D .; Aebischer, P.; Auwerx, J .; Rinsch, C. (2017-07-01). "Urolithin A e fanoang ka molomo e bolokehile ebile e hlophisa li-biomarker tsa mesifa le mitochondrial ho batho ba tsofetseng". Ntlafatso ea botsofaling. 1 (suppl_1): 1223–
[5] Heilman, Jacqueline; Andreux, Pénélope; Tran, Nga; Rinsch, Chris; Blanco-Bose, William (2017). "Tekolo ea polokeho ea urolithin A, metabolite e hlahisoang ke microbiota ea motho ka mpeng ha ho jeoa limela tse nkiloeng ke ellagitannins le ellagic acid". Lijo le Lik'hemik'hale Toxicology. EA-108-Pt A): 289– doi: 10.1016 / j.fct.2017.07.050. PMID 28757461.
