+ 86 (1812) 4514114 info@phcoker.com

Pfu ea Raw Flibanserin HCL (147359-76-0)

Raw Flibanserin hydrochloride powder, e rekisoang tlas'a lebitso la khoebo Addyi, ke meriana e amoheletsoeng bakeng sa phekolo ea ...


Boemo: Ka Phatlalatso ea Mesebetsi
Sehlopha: 25kg / Drum
Bokhoni: 1250kg / khoeli

Tlhaloso

Video ea Raw Flibanserin HCL (147359-76-0) video

Phofo ea Raw Flibanserin HCL (147359-76-0) Slitšobotsi

Name Product Flibanserin hydrochloride powder
Lebitso la lik'hemik'hale UNII-96XTC36K1B, 96XTC36K1B
Brand Name Addyi
Sehlopha sa Lithethefatsi Mohanyetsi oa mefuta e mengata ea serotonin agonist (MSAA)
Nomoro ea CAS 147359-76-0
InChIKey XGAGFLQFMFCIHZ-UHFFFAOYSA-N
limolek'hule Formula C20H22ClF3N4O
limolek'hule Wtse robeli 426.8630896
Masapo a monoisotopic 426.143 g / mol
Ho qhibiliha Poli > 225 ° C (qeto.)
Fho tsosolosa Poli Ha ho letsatsi le fumanehang
Likokoana-hloko tsa Half-Life dihora tse 11
Color Tšepe e tšoeu
Sho khoneha DMSO (Ntho e nyenyane), Methanol (Nyenyane)
Storage Tmocheso Mocheso oa kamore
Aho latela E thehiloe bakeng sa ho phekoloa bothata ba boikaketsi ba ho kopanela liphate ho ba basali.

Phofo e kholo ea Flibanserin HCL (147359-76-0) Tlhaloso

Flibanserin hydrochloride ke eona lithethefatsi tsa pele tse lokelang ho amoheloa bakeng sa bothata ba ho ba le takatso ea ho kopanela liphate (HSDD) ho basali ba pele ho tšoaetso ea FDA ka August 2015. Qalong e ile ea hlahisoa e le moriana o thibelang ho imeloa kelellong ke Boehringer Ingelheim, empa e bontša ho se sebetse hantle litsing 'me e ile ea ntlafatsoa ka ho fetisisa e le moriana oa boikaketsi oa ho kopanela liphate le sekhooa sa Sprout Pharmaceuticals. Mekhoa ea Flibanserin e bakoa ke hore e na le kamano e phahameng ea 5-HTA1 le 5-HTA2 e amohelang, e bontšang liketso tsa agonist ho 5-HTA1 le mohanyetsi oa 5-HTA2, e leng ho etsang hore ho theohe ha serotonin bokong hammoho le phello ea ho eketsa norepinephrine le dopamine neurotransmitters.

Flibanserin hydrochloride phofo (147359-76-0) Mehato ea Liketso

Flibanserin hydrochloride e sebetsa ka lik'hemik'hale tse tharo tsa bohlokoa tsa boko: dopamine, norepinephrine le serotonin. Lik'hemik'hale tsena ke li-neurotransmitters. Ba ikarabella ho romela lipontšo pakeng tsa boko le likarolo tse ling tsa 'mele ka tsamaiso ea methapo.

Dopamine le norepinephrine li ameha ka thabo ea thobalano. Leha ho le joalo, serotonin e kenya letsoho tabeng ea ho thibela ho kopanela liphate le ho fokotsa ho kopanela liphate ka koloi. Ho nahanoa hore haeba lik'hemik'hale tsena li sa leka-lekaneng - haeba litekanyetso tsa dopamine le tsa norepinephrine li le tlase haholo le / kapa li-serotonin li phahame haholo - mosali a ka ikutloa a sa rate letho ka thobalano.

Flibanserin hydrochloride e sebetsa ka ho phahamisa maemo a dopamine le norepinephrine ha e ntse e theola maemo a serotonin. Ka tsela ena, lik'hemik'hale tse thusang ho khothaletsa takatso ea ho kopanela liphate li eketsehile 'me e' ngoe e ka sitisang takatso e fokotsehile.

Ts'ebeliso ea phofo ea Raw Flibanserin HCL (147359-76-0)

Flibanserin hydrochloride ke mohanyetsi oa 5-HT1A le 5-HT2A e hlahisitsoeng bakeng sa phekolo ea bothata ba ho ba le takatso ea ho kopanela liphate ka ho kopanela liphate ho basali (1,2).

Morero oa Raw Flibanserin HCL (147359-76-0) e khothalletsoang.

100 mg ka molomo hang ka letsatsi nakong ea ho robala

Nako ea phekolo: Moriana ona o lokela ho emisoa ka mor'a libeke tsa 8 haeba mokuli a sa tlalehe ho ntlafatsa matšoao.

Litlhaloso: Meriana ena ha e bontšoe ho ntlafatsa tshebetso ea thobalano, 'me ha e bontšoe kalafo ho basali ba postmenopausal kapa banna.

Litla-morao tsa Flibanserin hydrochloride powder (147359-76-0)

Liketsahalo tse bohloko li tloaelehile har'a basali ba nkang flibanserin. Boholo ba liketsahalo tse bohloko li ne li le bonolo ho isa boemong bo itekanetseng. Liketsahalo tse bohloko tse tlalehiloeng ka kakaretso li kenyeletsa ho ba le botenya, ho nyekeloa ke pelo, ho ikutloa u khathetse, ho robala le bothata ba ho robala.

Ho noa joala nakong ea flibanserin ho ka baka khatello e matla ea mali (khatello e tlase ea mali e hlahisitseng matšoao ka mor'a likhalase tsa 2 tsa veine e hlahang 17%).


=

Shangke Chemical ke setsi se phahameng sa theknoloji se ikhethileng ka li-intermediate tse sebetsang tsa meriana (APIs). Ho laola boleng nakong ea tlhahiso, litsebi tse ngata tse nang le phihlelo, lihlahisoa tsa tlhahiso ea pele le li-laboratori ke lintlha tsa bohlokoa.

Contact