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L-Carnosine phofo (305-84-0)

L-Carnosine ke sethala se hahang sa liprotheine se hlahisoang ka tlhaho 'meleng. E fumanoa mesifa ha… f …….


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L-Carnosine phofo (305-84-0) video

L-Carnosine phofo (305-84-0) Slitšobotsi

Name Product L-Carnosine phofo
Lebitso la lik'hemik'hale beta-Alanyl-L-histidine

Karnozin

Carnosine

Brand Name L-Carnosine phofo
Sehlopha sa Lithethefatsi Peptide e khahlanong le botsofali
Nomoro ea CAS 305-84-0
InChIKey CQOVPNPJLQNMDC-ZETCQYMHSA-N
limolek'hule Formula C9H14N4O3
limolek'hule Wtse robeli 226.236 g · molâ'1
Masapo a monoisotopic 226.10659 g / mol
Ho qhibiliha Poli 253 ° C (dec.) (Lit.)
Fho tsosolosa Poli N / A
Likokoana-hloko tsa Half-Life N / A
Color White
Sho khoneha Qhibilihang ka metsing, le hoo e batlang e le pepeneneng
Storage Tmocheso 2-8 ° C
Aho latela

ke eng L-Carnosine?

L-Carnosine (beta-alanyl-L-histidine) ke sethopo sa amino acid beta-alanine le histidine. E kenelletse haholo linthong tsa mesifa le bokong.

L-Carnosine le carnitine li fumanoe ke setsebi sa chemistry sa Russia V.Gulevich.Bahlahlobisisi ba Borithane, Korea Boroa, Russia le linaheng tse ling ba bontšitse hore carnosine e na le thepa ea antioxidant e ka bang molemo. Carnosine e netefalitsoe ho fumanela mefuta ea oksijene e sebetsang (ROS) le alpha-beta unsaturatedaldehydes e thehiloeng ho peroxidation ea cell membrane ea mafura acid nakong ea khatello ea oxidative. Carnosine hape ke zitterion, molek'hule e sa jeleng paate e nang le pheletso e ntle le e mpe.

Joalo ka carnitine, carnosine e entsoe ka motso oa lentsoe carn, ho bolelang nama, ha e bua ka ho ata ha eona liprotheine tsa liphoofolo. Lijo tse nang le phepo ea limela (haholo-holo vegan) ha li na carnosine e lekaneng, ha li bapisoa le maemo a fumanoang lijong tse tloaelehileng.

Carnosine e ka kopitsa li-ions tsa tšepe tse arohaneng.

L-Carnosine e ka eketsa moeli oa Hayflick ho li-fibroblasts tsa motho, hammoho le ho hlaha ho fokotsa sekhahla sa telomere. Carnosine e boetse e nkoa e le geroprotector.

Melemo ea l-carnosine

  1. Mefuta e mecha ea kenyelletso ea lijo.
  2. Carnosine e entsoe ka β alanine le histidine dipeptide, liphoofolo li ka etsoa ka 'mele.
  3. Carnosine e bakoang ke li-radicals tsa mahala le li-ion tsa tšepe li sitisitsoe haholo ka lipid oxidation ha li sebetsa carnosine e ka thibela lipid oxidation, tšireletso ea mebala. Carnosine le phytic acid oxidation upinzani khomo. Lijo tse tlatsitsoeng ka 0.9 g / kg carnosine li ka ntlafatsa 'mala le ho ntlafatsa botsitso ba oxidative ea mesifa ea marapo, e na le phello ea synergistic le vithamini e.
  4. Ts'ebeliso ea litlolo e ka thibelang botsofe ba letlalo le sesoeu sesoeu, carnosine e ka thibela tšenyo e bakoang ke ho tsuba, e fetang mahlaseli a letsatsi a mahala a senya letlalo mme li-radical li-atom kapa li-radical tse sebetsang hantle haholo 'meleng oa motho. ho ba oxidation ea lintho tse ling 'meleng.
  5. Carnosine e na le antioxidant, e leng antioxidant ea tlhaho.
  6. Batho ba leng marang-rang a leihlo la mahlo a matla baa ntlafatsoa. E sebelisoa e le lisebelisoa tse tala ho li-carnosine antioxidant agents li ka phekola lefu la senile.
  7. Ntho e utloisang bohloko ea litlolo, e ka khothaletsa pholiso ea maqeba, haholo e sebelisoang kalafo ea kalafo ea meriana ea molomo.

melemo ea l-carnosine bakeng sa letlalo

  1. L-Carnosine phofo ke ea bohlokoa e le sehlahisoa se felisang botsofe ka lebaka la litlamorao ho lihlahisoa tsa pele tsa lihlahisoa tsa glycosylation (AGEs). Bacha ke liprotheine tse sa tloaelehang, tse amanang le sefapano le oxid tse ka 'nang tsa bapala karolo botsofaling.
  2. L-carnosine e thusa ho thibela khokahano ea "collagen" ea letlalo e lebisang ho lahleheng ha elasticity le wrinkles.
  3. L carnosine e sebetsa hape e le taolo ea likhakanyo tsa zinki le tsa koporo liseleng tsa methapo, e thusa ho thibela ho feteletsoa ke "li-neuroactive" 'meleng ho tiisa lithuto tsohle tse ka holimo mme lithuto tse ling li bontšitse melemo e meng.
  4. L Carnosine ke SuperAntiOxidant e emisang esita le lisebelisoa tse matla ka ho fetisisa tse sa senyeheng: The hydroxyl and peroxyl radicals, superoxide, le oxygen oxygen. Carnosine e thusa ho hlafuna litšepe tsa ionic (lintho tse chefo tse tsoang 'meleng).

Pure l-carnosine phofo ts'ebeliso le ts'ebeliso:

  1. E sireletsa li-membrane tsa lisele tsa epithelial ka mpeng ebe e li khutlisetsa ho metabolism ea tsona e tloaelehileng;
  2. E sebetsa joalo ka antioxidant hape e sirelletsa mpa ho tsoa taolong le tšenong e bakiloeng ke ho tsuba;
  3. E na le thepa ea anti-inflammatory le moderates tlhahiso ea interleukin-8;
  4. Ho latela ulcerations, e sebetsa e le tšitiso lipakeng tsa bona le asiti ea mala mme e thusa ho ba folisa.

Tlhaloso:

  1. L-carnosine e le mokhoa oa ho sebetsana le fluvoxamine kalafong ea bokuli bo ikemetseng: Phuputso e sa sebetseng ea mahlo a mabeli. Arabzadeh S et al. Hum Psychopharmacol. (2017)
  1. Physiology le pathophysiology ea carnosine. Boldyrev AA et al. Physiol Rev. (2013)
  1. Litholoana tsa L-Carnosine tse itšetlehang ka litla-morao tsa kutloelo-bohloko ea mesifa le phallo ea mali. Horii Y et al. Neurosci Lett. (2015)
  1. Tlhahiso ea nalane ea sefahleho e nang le "Carnosine Inhibits" Tlhabollo ea Lihlahisoa tsa Bofelo bo Tsoetseng Pele ba Glycation Letlalong la Motho. Narda M et al. Letlalo Pharmacol Physiol. (2018)
  1. Mesebetsi ea tlhaho ea pididole ea tlhaho e nang le peptidomimetics n-acetylcarnosine, carcinine le L-carnosine ho lihlahisoa tsa tlhokomelo ea mahlo le letlalo. Babizhayev MA et al. Bophelo ba Saense. (2006)
  1. Ho nchafatsa sefahleho sa sefahleho le sehlahisoa se seng sa 'mele se khahlanong le ho tsofala: thuto e bulehileng eo u ka e fumanang. Garre A et al. Clin cosmet Inarcher Dermatol. (2017)

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


Litlhaloso le lihlahisoa tsa lihlahisoa