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Oli e kholo ea Avanafil (330784-47-9)

Avanafil phofo e sebelisetsoa ho phekola banna ba nang le bothata ba ho hlonama (hape bo bitsoang ho hloka thobalano). Avanafil ke ea sehlopha sa …… ..


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Sehlopha: 25kg / Drum
Bokhoni: 1290kg / khoeli

Tlhaloso

Phala e kholo ea Avanafil (330784-47-9) video

Mofuta o moholo oa Avanafil (330784-47-9) Tlhaloso

Raw Avanafil phofo ke inhibitor ea PDE5 e amoheloang bakeng sa tahi (ED: impotence; ho sitoa ho fumana kapa ho boloka erection ho banna). Raw Avanafil phofo e sebetsa ka ho thibela mofuta o itseng oa phosphodiesterase 5 enzyme e fumanehang liseleng tse fapaneng tsa 'mele, empa haholoholo ho corpus cavernosum penis, hammoho le retina. E sebetsa ka ho eketsa phallo ea mali ho ea botoneng nakong ea takatso ea thobalano. Lithethefatsi tse ling tse tšoanang ke sildenafil, tadalafil le vardenafil. Monyetla oa phofo ea Raw Avanafil ke hore e na le ts'ebetso e potlakileng haholo ea ts'ebetso ha e bapisoa le li-inhibitors tse ling tsa PDE5. E kenoa ka potlako, e fihla molemong oa ho qeta boholo ba metsotso ea 30-45.Ka karolo ea bobeli borarong ea barupeluoa ba khonne ho etsa ketso ea thobalano nakong ea metsotso ea 15.

Oli e kholo ea Avanafil (330784-47-9) Slitšobotsi

Name Product Oli e nyenyane ea Avanafil
Lebitso la lik'hemik'hale 330784-47-9;STENDRA; (s)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide; TA 1790; TA-1790
Brand Name Stendra le Spedra
Sehlopha sa Lithethefatsi PDE5 inhibitor
Nomoro ea CAS 330784-47-9
InChIKey WEAJZXNPAWBCOA-INIZCTEOSA-N
limolek'hule Formula C23H26ClN7O3
limolek'hule Wtse robeli 483.95
Masapo a monoisotopic 483.179 g / mol
Ho qhibiliha Poli 150-152 ° C
Fho tsosolosa Poli Ha ho dintlha tse fumanehang
Likokoana-hloko tsa Half-Life Nako ea ho felisa halofo ea bophelo = 5.36 - Lihora tsa 10.66
Ponahalo Pula e tšoeu
Sho khoneha DMSO, Methanol
Storage Tmocheso Boloka ho 4 ° C
kopo Phosphodiesterase (PDE5) inhibitor, e sebelisetsoang ho phekola ho se sebetse hantle.

Mofuta o moholo oa Avanafil (330784-47-9) Tlhaloso

Avanafil e sebelisetsoa ho phekola khatello ea kelello (ED: impotence; ho sitoa ho fumana kapa ho boloka sebopeho ho banna). Avanafil phofo e sehlopheng sa meriana e bitsoang li-inhibitors tsa phosphodiesterase (PDE). E sebetsa ka ho eketsa phallo ea mali ho ea botoneng nakong ea takatso ea thobalano. Ho phalla ha madi ho eketsehileng hona ho ka baka hore motho a emisoe. Phofo ea Avanafil ha e phekole khatello ea kelello kapa ho eketsa takatso ea thobalano. Avanafil ha e thibele ho ima kapa ho ata ha mafu a tšoaetsanoang ka ho kopanela liphate a kang vaerase ea HIV.

Avanafil phofo (330784-47-9) Mokhoa oa Ketso

Avanafil ke phosphodiesterase 5 (PDE5) inhibitor e sebelisang kalafo ea kalafo e bakoang ke lefu la tsoekere, khatello ea kelello ea khatello ea kelello le mathata a mang. Avanafil e thibela mofuta oa "cGMP" oa phosphodiesterase e khethehileng 5 (PDE5) e ikarabellang bakeng sa ho nyenyefatsa cGMP ka har'a covernosum e fumanehang haufi le botoneng. Phekolo ea penile nakong ea ts'usumetso ea thobalano e bakoa ke ho phalla hoa mali ha penile ho bakoang ke ho phomola ha methapo ea methapo le mesifa e boreleli ea covernosal. Karabelo ena e kopantsoe le ho lokolloa ha nitric oxide (NO) litsing tsa methapo ea kutlo le lisele tsa endothelial, tse tsosang phello ea cGMP liseleng tsa mesifa e boreleli. Cyclic GMP e etsa hore mesifa e phutholohe 'me e eketsehe ha mali a phalla ka har'a corpus cavernosum. Thibelo ea mofuta oa phosphodiesterase 5 (PDE5) ka avanafil e ntlafatsa ts'ebetso ka ho eketsa palo ea cGMP.

Kopo ea Avanafil powder (330784-47-9)

Avanafil phofo e sebelisetsoa ho phekola banna ba nang le bothata ba ho hlonama (hape bo bitsoang ho hloka thobalano).

Ho khothalletsoa Avanafil powder (330784-47-9) Nako

Bakeng sa batho ba bangata, tlhahiso e khothalletsoang ho qala ka avanafil powder ke 100 mg ka letsatsi e nkiloeng ka metsotso ea 30 pele ho thobalano. Ho itšetlehile ka ho lekaneng ha karabelo kapa litla-morao, tekanyo e ka eketsoa ho 200 mg kapa ea fokotseha ho ea ho 50 mg ka letsatsi. Batho ba noang meriana e eketsang ka mokhoa o itekanetseng mali a avanafil ha baa lokela ho feta tekanyo ea 50 mg lihora tsa 24 (Bona likamano tsa lithethefatsi).

Melemo ea Avanafil powder (330784-47-9)

Khaotsa ho sebelisa avanafil mme u letse ngaka hang-hang haeba u na le:

▪ pono e fetoha, tahlehelo ea pono ka tšohanyetso;

▪ ho lla litsebeng tsa hao, kapa ho lahleheloa ke maikutlo kapele;

▪ bohloko, ho ruruha, mofuthu kapa bofubelu ka leoto kapa maoto ka bobeli;

▪ phefumoloho e khutšoanyane, ho ruruha matsohong kapa maotong;

▪ boikutlo bo nang le molumo, joalo ka ha u ka feta; kapa

▪ ho hlajoa ha penis e bohloko kapa e qetella lihora tsa 4 kapa nako e telele.

Litla-morao tse tloaelehileng li kenyeletsa:

▪ hlooho;

▪ ho ruruha (mofuthu, bofubelu, kapa boikutlo ba maikutlo);

▪ matšoao a batang a kang nko kapa nko e bohloko, 'metso; kapa

▪ bohloko bo bohloko.


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Litlhaloso le lihlahisoa tsa lihlahisoa

Lipotso tsa 9 ho ipotsa pele u nka Avanafil

References

  1. Ryan M Burke, Jeffery D Evans, Avanafil bakeng sa kalafo ea tahi: tlhahlobo ea bokhoni ba eona, Vasc Health Risk Manag. 2012; 8: 517-523.
  2. DeRogatis LR, Burnett AL. Seoa sa mafu a seoa. J Sex Med. 2008; 5: 289-300.
  3. Zhao C, Kim S, Yan D, et al. Ho sebetsa hantle le polokeho ea avanafil bakeng sa ho phekola ho se sebetse hantle: liphetho tsa liteko tse sa laoloeng, tse sa sebetseng, tse foufetseng habeli, tse laoloang ke sebaka. BJU Int. 2012 Mar 27;

Shangke Chemical ke setsi se phahameng sa theknoloji se ikhethileng ka li-intermediate tse sebetsang tsa meriana (APIs). Ho laola boleng nakong ea tlhahiso, litsebi tse ngata tse nang le phihlelo, lihlahisoa tsa tlhahiso ea pele le li-laboratori ke lintlha tsa bohlokoa.

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