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Raw Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

Raw Lorcaserin hydrochloride hemihydrate powder ke .......


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Raw Lorcaserin hydrochloride hemihydrate powder (856681-05-5) video

Raw Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Lintlha tse ling

Name Product Raw Lorcaserin hydrochloride hemihydrate powder
Lebitso la lik'hemik'hale Lorcaserin hydrochloride, (R) -8-chloro-1-methylene-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate; (R) -8-chloro-2,3,4,5-tetrahydro-1-methylene-1h-3-benzazepine hydrochloride hemihydrate
Brand Name Belviq
Sehlopha sa Lithethefatsi 5-HT2C receptor inhibitor
Nomoro ea CAS 856681-05-5
InChIKey WRZCAWKMTLRWPR-VSODYHHCSA-N
limolek'hule Formula C22H32Cl4N2O
limolek'hule Wtse robeli 482.31
Masapo a monoisotopic 480.1268745
Ho qhibiliha Poli Ha ho dintlha tse fumanehang
Fho tsosolosa Poli Ha ho dintlha tse fumanehang
Likokoana-hloko tsa Half-Life Lorcaserin e na le bophelo ba halofo ea mali ea ~ lihora tse 11
Color Pula e tšoeu
Solubility Metsi a Matsoeliso 0.0709 mg / mL
Storage Tmocheso Ha ho dintlha tse fumanehang
Aho latela Raw Lorcaserin hydrochloride hemihydrate phofo e sebelisitsoeng e le lithethefatsi tse khahlanong le botenya. E na le karolo ea ho nyahamisa takatso ea lijo le serotonergic agonist.

Raw Lorcaserin hydrochloride hemihydrate phofo (856681-05-5) Tlhaloso

Lorcaserin hydrochloride hemihydrate powder ke hydrate ke mofuta oa hemihydrate oa lorcaserin hydrochloride. E sebelisoa e le lithethefatsi tse khahlanong le botenya. E na le karolo ea ho nyahamisa takatso ea lijo le serotonergic agonist. E na le lorcaserin hydrochloride.

Raw Lorcaserin hydrochloride hemihydrate phofo e sebelisoa ho phekola botenya bo amanang le k'holeseterole e phahameng, khatello e phahameng ea mali, kapa mofuta oa 2 lefu la tsoekere.

FDA e amohetse phofo ea Raw Lorcaserin hydrochloride hemihydrate bakeng sa batho ba mafura haholo (ka boima ba 'mele, kapa BMI, ea 30 kapa e phahameng) kapa ba boima haholo (ba nang le BMI ea 27 kapa ka holimo) hape ba na le botebo bo le bong- tse amanang le bophelo bo botle joaloka mofuta oa 2 lefu la tsoekere, khatello e phahameng ea mali kapa k'holeseterole e phahameng.

Raw Lorcaserin hydrochloride hemihydrate powder e sebetsa ka ho laola takatso ea lijo-haholo-holo ka ho etsa hore li-receptor li fumane bokooa bakeng sa serotonin, e leng neurotransmitter e etsang hore motho a ikutloe a sa khotsofala. Serotonin e boetse e ameha maikutlo; meriana e mengata ea ho itšireletsa e sebetsa ka ho thibela ho tsosolosoa ha serotonin le ho boloka boko bo amohelehang lik'hemik'hale. Bafuputsi ba Arena ba re lithethefatsi tsa bona li etselitsoe ho batla feela batho ba amohelang serotonin tse amang takatso ea lijo.

Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Mehato ea Ketso

Ho lumeloa hore Lorcaserin e fokotsa lijo le ho khothaletsa ho satiety ka ho hlahisa li-receptor tsa 5-HT2C tse nang le li-pro-opiomelanocortin neurons tse nang le li-anorexigen tse fumanehang hypothalamus. Mokhoa o tobileng oa ketso ha o tsejoe.

Lorcaserin ka tekanyo e khothalletsoang letsatsi le leng le le leng e sebelisana le li-receptor tsa 5-HT2C ha li bapisoa le li-receptors tsa 5-HT2A le 5-HT2B (sheba Table 5), tse ling tsa 5-HT receptor subtypes, le transporter ea 5-HT ea mochine, le libaka tsa 5-HT .

kopo ea Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

  • Ho tepella takatso ea lijo: Moemeli ea sebelisetsoang ho fokotsa takatso ea lijo.
  • serotonergic agonist: Moemeli ea nang le kamano e haufi le serotonin receptors 'me o khona ho etsisa liphello tsa serotonin ka ho susumetsa mosebetsi oa physiologic li-receip cell. Li-agonists tsa Serotonin li sebelisoa e le ho imeloa kelellong, ho tšoenyeha ha maikutlo le ho phekola mafu a migraine.

Recommended Lorcaserin hydrochloride hemihydrate phofo (856681-05-5)

Kaha tlhahisoleseding e nepahetseng mabapi le tšebeliso ea Lorcaserin hydrochloride hemihydrate e sitoa ho fumanoa, tlhahiso-leseling e latelang ke bakeng sa boitsebiso feela:

Pfu ea Lorcaserin HCL 846589-98-8 e kena ka foromo ea lipolisi 'me e nkoa ka tloaelo ka linako tse ling 1-2 ka letsatsi, ka ntle kapa ntle le lijo. Lorcaserin e tlameha ho sebelisoa hammoho le lijo tse fokotsehileng tsa khalori le moralo oa ho ikoetlisa.

Palo e khothalletsoang ea lorcaserin ke 10 mg e tsamaisoang ka molomo habeli ka letsatsi. Lorcaserin e ka nkoa ntle ho lijo. Lorcaserin e lokela ho khaotsa ho bakuli ba hlōlehang ho finyella bonyane 5% boima ba boima ba 'mele ka beke 12 ha bakuli bana ba sa khone ho ba le tahlehelo ea boima ba' mele le phekolo e tsoelang pele.

Melemo ea ho Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

Lorcaserin hydrochloride hemihydrate powder ke 5-HT2C receptor agonist eo ho nahanoang hore e fokotseha ho ja lijo ka har'a mokhoa oa POMC. Litlhoko tsa phofo tsa Lorcaserin HCL:

  • Lorcaserin hydrochloride hemihydrate phofo e sebelisoa hammoho le ho ja le ho ikoetlisa ho phekola botenya.
  • Ka linako tse ling Lorcaserin hydrochloride hahydrate e phofo e sebelisoa ho phekola botenya bo ka 'nang ba amana le lefu la tsoekere, k'holeseterole e phahameng kapa khatello ea mali e phahameng.
  • Lorcaserin hydrochloride hemihydrate phofo e ke ke ea sebetsana le boemo bo botle ba bophelo bo botle (tse kang lefu la pelo, lefu la tsoekere, khatello ea mali e phahameng).

Litla-morao ea Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

Lorcaserin hydrochloride hemihydrate phofo e sebelisetsoa ho phekoloa ho laola boima bo boima ho batho ba baholo ba nang le boima ba 'mele (BMI) ea 30 kapa e kholoanyane (e bobebe) e le ho eketsa lijo tse fokotsehileng tsa khalori le ho ikoetlisa. E boetse e lumelloa ho sebelisoa ke batho ba baholo ba nang le BMI ea 27 kapa e kholoanyane (ho feta boima ba 'mele) le bao bonyane ba amanang le boima ba mali bo kang khatello e phahameng ea mali (khatello ea mali), kapa k'holeseterole e phahameng (dyslipidemia). Leha ho le joalo, e ka ba le litla-morao tse ling. E ka tlaase mona:

Tlitla-morao tse tloaelehileng haholo:

  • -Ke hlahlamang,
  • -Boiketsi,
  • -Fatigue,
  • -Ba baka,
  • -Khala molomo,
  • -Constipation, le
  • -Hygoglycemia (tsoekere e tlaase ea mali).

Litla-morao tse ling tse tloaelehileng empa tse tebileng tse amanang le lorcaserin li kenyelletsa:

  • -Bala mathata a li-valve,
  • -Ka ho ela hloko kapa ho hopola,
  • Mathata a kelello,
  • -Khatello kapa maikutlo a ho ipolaea,
  • -Ke likhetho tse ntle,
  • -Ka otla pelo,
  • -A theohela palo ea lisele tsa mali, le
  • -Ka eketseha ha hormone, prolactin.


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